Comparative Study Matching Intraperitoneal Onlay Mesh (IPOM) and Sublay Mesh to Treat Umbilical Hernia

NCT ID: NCT01201564

Last Updated: 2019-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE4

Total Enrollment

306 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-07-31

Study Completion Date

2018-12-31

Brief Summary

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This study is designed to compare two techniques for operative care of umbilical hernia in adults regarding wound complications, wound side fluid collections, recurrence rate, postoperative pain, duration of hospitalization and quality of life. The IPOM technique provides mesh positioning directly into the abdominal cavity onto the defect under laparoscopic control while in sublay position the mesh is placed directly behind the rectus muscle after small incision close to the belly button.

Detailed Description

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Conditions

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Umbilical Hernia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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intraperitoneal onlay mesh repair

Group Type ACTIVE_COMPARATOR

intraperitoneal onlay mesh repair

Intervention Type PROCEDURE

The IPOM technique provides mesh positioning directly into the abdominal cavity onto the defect under laparoscopic control while in sublay position the mesh is placed directly behind des rectus muscle after small incision close to the belly button.

sublay mesh repair

Group Type ACTIVE_COMPARATOR

sublay mesh repair

Intervention Type PROCEDURE

The IPOM technique provides mesh positioning directly into the abdominal cavity onto the defect under laparoscopic control while in sublay position the mesh is placed directly behind des rectus muscle after small incision close to the belly button.

Interventions

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intraperitoneal onlay mesh repair

The IPOM technique provides mesh positioning directly into the abdominal cavity onto the defect under laparoscopic control while in sublay position the mesh is placed directly behind des rectus muscle after small incision close to the belly button.

Intervention Type PROCEDURE

sublay mesh repair

The IPOM technique provides mesh positioning directly into the abdominal cavity onto the defect under laparoscopic control while in sublay position the mesh is placed directly behind des rectus muscle after small incision close to the belly button.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* informed consent
* patient age: ≥ 18 years
* elective surgery for umbilical hernia
* hernia diameter ≥ 1cm

Exclusion Criteria

* previous history of median laparotomy
* navel site infection
* contraindication for general anaesthesia
* American Society of Anesthesiologists (ASA) score \>IV
* pregnancy
* cirrhosis of the liver (CHILD B and C) and/or ascites
* cytostatic therapy
* incarcerated hernia
* recurrent hernia
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Clinical Trial Unit, University Hospital Basel, Switzerland

OTHER

Sponsor Role collaborator

University Hospital, Basel, Switzerland

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Daniel Oertli, Professor

Role: STUDY_CHAIR

Departement of General Surgery, University Hospital Basel, Switzerland

Oleg Heizmann, MD

Role: STUDY_DIRECTOR

Departement of General,- Visceral- and Thoracic Surgery, Diakoniekrankenhaus Rotenburg (Wuemme), Germany

Daniel Matz, MD

Role: PRINCIPAL_INVESTIGATOR

Departement of General,- Visceral- and Thoracic Surgery, Diakoniekrankenhaus Rotenburg (Wuemme), Germany

Locations

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Diakoniekrankenhaus Rotenburg (Wuemme) gGmbH

Rotenburg (Wümme), Lower Saxony, Germany

Site Status

University Hospital Basel

Basel, , Switzerland

Site Status

Luzerner Kantonsspital

Lucerne, , Switzerland

Site Status

Countries

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Germany Switzerland

References

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Benhidjeb T, Benecke C, Strik MW. [Incisional hernia repair: sublay or intraperitoneal onlay mesh (IPOM)?]. Zentralbl Chir. 2008 Sep;133(5):458-63. doi: 10.1055/s-2008-1076954. Epub 2008 Oct 15. German.

Reference Type BACKGROUND
PMID: 18924044 (View on PubMed)

Lau H, Patil NG. Umbilical hernia in adults. Surg Endosc. 2003 Dec;17(12):2016-20. doi: 10.1007/s00464-003-9027-7. Epub 2003 Oct 28.

Reference Type BACKGROUND
PMID: 14574545 (View on PubMed)

Mayo WJ. VI. An Operation for the Radical Cure of Umbilical Hernia. Ann Surg. 1901 Aug;34(2):276-80. doi: 10.1097/00000658-190107000-00021. No abstract available.

Reference Type BACKGROUND
PMID: 17861015 (View on PubMed)

Luijendijk RW, Hop WC, van den Tol MP, de Lange DC, Braaksma MM, IJzermans JN, Boelhouwer RU, de Vries BC, Salu MK, Wereldsma JC, Bruijninckx CM, Jeekel J. A comparison of suture repair with mesh repair for incisional hernia. N Engl J Med. 2000 Aug 10;343(6):392-8. doi: 10.1056/NEJM200008103430603.

Reference Type BACKGROUND
PMID: 10933738 (View on PubMed)

Venclauskas L, Silanskaite J, Kiudelis M. Umbilical hernia: factors indicative of recurrence. Medicina (Kaunas). 2008;44(11):855-9.

Reference Type BACKGROUND
PMID: 19124962 (View on PubMed)

Hilling DE, Koppert LB, Keijzer R, Stassen LP, Oei IH. Laparoscopic correction of umbilical hernias using a transabdominal preperitoneal approach: results of a pilot study. Surg Endosc. 2009 Aug;23(8):1740-4. doi: 10.1007/s00464-008-0177-5. Epub 2008 Nov 18.

Reference Type BACKGROUND
PMID: 19015918 (View on PubMed)

Forbes SS, Eskicioglu C, McLeod RS, Okrainec A. Meta-analysis of randomized controlled trials comparing open and laparoscopic ventral and incisional hernia repair with mesh. Br J Surg. 2009 Aug;96(8):851-8. doi: 10.1002/bjs.6668.

Reference Type BACKGROUND
PMID: 19591158 (View on PubMed)

Bullinger M. [Assessment of health related quality of life with the SF-36 Health Survey]. Rehabilitation (Stuttg). 1996 Aug;35(3):XVII-XXVII; quiz XXVII-XXIX. German.

Reference Type BACKGROUND
PMID: 8975342 (View on PubMed)

Other Identifiers

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IPOM-46/10

Identifier Type: -

Identifier Source: org_study_id

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