Long-term Follow-up of Incisional Hernia Repaired With Intraperitoneal Mesh

NCT ID: NCT00891254

Last Updated: 2012-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-01-31

Study Completion Date

2012-07-31

Brief Summary

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The intraperitoneal repair has been proven safe for the repair of incisional hernia and is accepted, together with the subfascial or retromuscular repair as the "gold-standard" for the repair of incisional hernia. However no studies have convincingly proven that this approach is better than the on-lay repair.

The authors believe that the intraperitoneal repair performs better than the on-lay repair for incisional hernia.

Detailed Description

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Conditions

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Incisional Hernia

Keywords

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Incisional hernia Intraperitoneal mesh repair On-lay repair Prosthetic mesh First repair (no recurrent hernia will be included) Recurrence Complications

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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1. Intraperitoneal repair

Patients with incisional hernia, 5 cm in diameter or with an area of 25 cm2, submitted to elective surgery

Group Type ACTIVE_COMPARATOR

Implant of a prosthetic mesh

Intervention Type DEVICE

A prosthetic mesh will be implanted either intraperitoneally or in the on-lay (supra-fascial) position depending on the arm of the study

2. On-Lay repair

Patients with incisional hernia, with a diameter of 5 cm or an area of 25 cm2, submitted to elective surgery

Group Type ACTIVE_COMPARATOR

Implant of a prosthetic mesh

Intervention Type DEVICE

A prosthetic mesh will be implanted either intraperitoneally or in the on-lay (supra-fascial) position depending on the arm of the study

Interventions

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Implant of a prosthetic mesh

A prosthetic mesh will be implanted either intraperitoneally or in the on-lay (supra-fascial) position depending on the arm of the study

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients with incisional hernia 5 cm of diameter or with an area of 25 square cm (cm2)
* First repair
* Older than 35 years of age and younger than 75 years of age
* Both genders
* Any BMI
* Only upper abdominal midline incisional hernias (supraumbilical)
* Patients submitted only to elective repair

Exclusion Criteria

* Recurrent incisional hernia
* Emergency surgery
* Hernias with a diameter higher than 5 cm or more than 25 cm2 of area
* Lower midline abdominal incisional hernias
* Other hernias rather than midline incisional hernias
* Non-incisional hernias
Minimum Eligible Age

35 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cirujanos la Serena

OTHER

Sponsor Role lead

Responsible Party

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MARCELO A. BELTRAN, M.D.

DIGESTIVE SURGEON

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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MARCELO A BELTRAN, M.D.

Role: PRINCIPAL_INVESTIGATOR

Hospital de La Serena

Locations

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Hospital de La Serena

La Serena, Coquimbo Region, Chile

Site Status

Countries

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Chile

Other Identifiers

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HLS-2904009-03

Identifier Type: -

Identifier Source: org_study_id