Proportional Assist Ventilation vs Pressure Support Ventilation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-11-30

Study Completion Date

2010-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

In this study, we want to compare two different kinds of artificial ventilation to see if one encourages faster weaning from breathing support and if one provides better sleep quality. These artificial ventilation types are:

1. Pressure support ventilation; the standard ventilation that we use for the patients in the Respiratory Acute Care Unit. Pressure support ventilation ventilators use constant air pressure to assist patients with their breathing.
2. Proportional assist ventilation; a newer way of helping people with their breathing. The air pressure provided by proportional assist ventilation ventilators varies with the size of the breath that a person takes.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study

NCT02447692

Critically Ill Acute Respiratory Failure

COMPLETED NA

Effect of Variable PSV in Acute Lung Injury: Part I and Part II

NCT01683669

Acute Lung Injury (ALI) Acute Distress Respiratory Syndrome (ARDS)

COMPLETED NA

Variable Pressure Support Trial

NCT01769053

Acute Lung Injury Adult Respiratory Distress Syndrome at Least 24 h of Controlled Mechanical Ventilation

TERMINATED NA

VSV Versus PSV as a Weaning Mode of Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients

NCT03278795

COPD

UNKNOWN NA

Comparison of Weaning on Pressure Support vs. Proportional Assist Ventilation: A Pilot Study

NCT01666054

Weaning From Mechanical Ventilation

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Respiration, Artificial

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

PAV

Proportional Assist Ventilation will be used as a mechanical ventilation method for randomized patients in RACU

Group Type OTHER

Proportional Assist Ventilation

Intervention Type OTHER

Proportional Assist Ventilation will be used to ventilate the patients.

PS

Pressure Support Ventilation will be used as a mechanical ventilation method for randomized patients in RACU

Group Type OTHER

Pressure Support Ventilation

Intervention Type OTHER

Pressure Support ventilation will be used to ventilate the patients.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Proportional Assist Ventilation

Proportional Assist Ventilation will be used to ventilate the patients.

Intervention Type OTHER

Pressure Support Ventilation

Pressure Support ventilation will be used to ventilate the patients.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Tracheotomized or endotracheally intubated and mechanically ventilated patients transferred or scheduled to be transferred to the RACU.
* Age 18 years or older.

Exclusion Criteria

* Patients who are weaned from ventilatory support within the first 72 hours of transfer to the RACU. Even though these patients had been randomized, they will be excluded. They will be considered in the intention to treat analysis but the final outcome analysis will be performed after their exclusion.
* High spinal cord injury
* Immunosuppressed patients receiving chemotherapy or radiation therapy (\< 2 months after chemotherapy or radiation therapy).
* Neuromuscular/ neurological disease of a progressive nature resulting in chronic ventilator dependence.
* High risk of mortality within 3 months (severe neurological damage and cancer patients in terminal stages of the disease).
* Patients unable to trigger the ventilator for any reason.
* Any patient who is not considered a candidate for weaning from ventilatory support
* Patients consented for another interventional study.
* Patients requiring more than 30 days to wean once randomized will be excluded. They will be considered in the intention to treat analysis but the final outcome analysis will be performed after their exclusion.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No