Clinical Trials

NCT05902598 | ACTIVE_NOT_RECRUITING | PHASE3
37 Participants

A Phase 3 Study of VSA001 in Chinese Adults With Familial Chylomicronemia Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-07-10
Completion: 2024-11-26
Conditions
Familial Chylomicronemia Syndrome
Interventions
DRUG
No Results Yet
NCT05876377 | COMPLETED
1 Participants

Use and Effectiveness of COVID-19 Vaccines Using State Vaccine Registries and Insurance Claims Data

Study Type: OBSERVATIONAL
Last Updated: 2025-11-06
Start Date: 2023-10-23
Completion: 2025-09-09
Conditions
SARS-CoV-2 COVID-19 Post-Acute COVID-19 Syndrome
Interventions
BIOLOGICAL
No Results Yet
NCT05869552 | RECRUITING | NA
1485 Participants

Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-07-13
Completion: 2027-03-31
Conditions
Suicide Suicidal Ideation
Interventions
OTHER
No Results Yet
NCT05864157 | RECRUITING | NA
45 Participants

Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-08-16
Completion: 2026-05-01
Conditions
Parkinson Disease
Interventions
OTHER
No Results Yet
NCT05845918 | ACTIVE_NOT_RECRUITING | NA
45 Participants

PRogram to Improve Stress-levels and Enhance Memory

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-02-21
Completion: 2025-09-22
Conditions
Mild Cognitive Impairment
Interventions
BEHAVIORAL
No Results Yet
NCT05838482 | RECRUITING
100 Participants

Clinical Feasibility and Evaluation of Silicon Photon Counting CT

Study Type: OBSERVATIONAL
Last Updated: 2025-11-06
Start Date: 2023-09-07
Completion: 2026-06-30
Conditions
CT Photon-Counting
Interventions
DEVICE
No Results Yet
NCT05835505 | RECRUITING | PHASE2
28 Participants

Detoxification of the Liver In PSC (Dolphin)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-12-12
Completion: 2026-06-01
Conditions
Primary Sclerosing Cholangitis
Interventions
DRUG
No Results Yet
NCT05824702 | COMPLETED | NA
241 Participants

A Social Network Approach for Improving Medication Assisted Treatment and HIV Prevention and Medical Care Among People Who Inject Drugs in Ukraine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-09-20
Completion: 2025-09-01
Conditions
HIV
Interventions
BEHAVIORAL
No Results Yet
NCT05804383 | COMPLETED | PHASE1
51 Participants

A Multiple Ascending Dose Study in Healthy Volunteers and Patients With Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-03-28
Completion: 2025-07-15
Conditions
Alzheimer's Disease
Interventions
DRUG
No Results Yet
NCT05798611 | TERMINATED | PHASE2
36 Participants

Study of ART0380 in Patients With Biologically Selected Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-09-06
Completion: 2024-11-15
Conditions
Advanced Solid Tumor Recurrent Endometrial Cancer Metastatic Cancer
Interventions
DRUG
No Results Yet
NCT05772546 | ACTIVE_NOT_RECRUITING | PHASE2
60 Participants

Avatrombopag vs. Placebo for CIT in GI Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-11-01
Completion: 2025-12-31
Conditions
Gastrointestinal Cancer Gastrointestinal Neoplasms Chemotherapy-Induced Thrombocytopenia
Interventions
DRUG
No Results Yet
NCT05756088 | WITHDRAWN
0 Participants

Determining the Association of Microvascular Disease as Assessed by PET and Graft Injury by Donor Derived Cell Free DNA

Study Type: OBSERVATIONAL
Last Updated: 2025-11-06
Start Date: 2025-12-31
Completion: 2030-06-30
Conditions
Cardiac Allograft Vasculopathy Endothelial Dysfunction Microvascular Coronary Artery Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05730439 | COMPLETED | EARLY_PHASE1
71 Participants

Examining the Impact of Nicotine Pouches in Rural Ohio and Ohio Appalachia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-05-19
Completion: 2024-01-30
Conditions
Tobacco-Related Carcinoma
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT05711667 | ACTIVE_NOT_RECRUITING | PHASE3
105 Participants

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2024-07-11
Completion: 2029-06-30
Conditions
Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm
Interventions
PROCEDURE DRUG
No Results Yet
NCT05703269 | RECRUITING | NA
244 Participants

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-07-11
Completion: 2028-03-31
Conditions
NSCLC Renal Cell Carcinoma Breast Carcinoma Melanoma Brain Metastases, Adult Non-small Cell Lung Cancer SCLC Small-cell Lung Cancer
Interventions
RADIATION
No Results Yet
NCT05696626 | RECRUITING | PHASE3
500 Participants

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-10-31
Completion: 2027-04-30
Conditions
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT05681715 | COMPLETED | PHASE3
62 Participants

A Phase 3, Open-label, Crossover Study to Evaluate Self-administration of Rozanolixizumab by Study Participants With Generalized Myasthenia Gravis (gMG)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-04-17
Completion: 2024-04-23
Conditions
Generalized Myasthenia Gravis
Interventions
DRUG
NCT05681702 | RECRUITING | PHASE4
90 Participants

Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-02-15
Completion: 2026-01-31
Conditions
Coronary Artery Disease
Interventions
DRUG
No Results Yet
NCT05675449 | RECRUITING | PHASE1
90 Participants

A Clinical Trial of Four Medicines (Elranatamab Plus Carfilzomib and Dexamethasone or Maplirpacept) in People With Relapsed Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2022-12-14
Completion: 2026-04-22
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05669950 | RECRUITING | PHASE1/PHASE2
42 Participants

A Trial of Lu AG13909 in Participants With Congenital Adrenal Hyperplasia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2022-12-19
Completion: 2026-09-30
Conditions
Congenital Adrenal Hyperplasia
Interventions
DRUG
No Results Yet
NCT05668741 | RECRUITING | PHASE1/PHASE2
39 Participants

A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-02-27
Completion: 2026-12-23
Conditions
Cystic Fibrosis
Interventions
DRUG
No Results Yet
NCT05623774 | COMPLETED | PHASE1
64 Participants

A Dose Calibration Study Comparing IkT-001Pro to Imatinib Mesylate 400mg

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2022-12-16
Completion: 2024-06-30
Conditions
CML
Interventions
DRUG
No Results Yet
NCT05623306 | RECRUITING | NA
10 Participants

SEEG-Guided DBS for OCD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-04-13
Completion: 2026-03-01
Conditions
Obsessive-Compulsive Disorder
Interventions
DEVICE
No Results Yet
NCT05566795 | RECRUITING | PHASE3
400 Participants

DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-02-27
Completion: 2026-02-28
Conditions
Low-grade Glioma Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma Pediatric Low-grade Glioma
Interventions
DRUG
No Results Yet
NCT05556824 | RECRUITING | PHASE2
247 Participants

Multi-Center Study of Panosyl-Isomaltooligosaccharides Adjunctive to PPI Therapy to Treat GERD

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-03-03
Completion: 2026-03-31
Conditions
Gastroesophageal Reflux
Interventions
DRUG OTHER
No Results Yet
NCT05551741 | ACTIVE_NOT_RECRUITING | PHASE1
40 Participants

A First in Human Study of IBC-Ab002 in Persons With Early Alzheimer's Disease (AD)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-02-23
Completion: 2025-11-01
Conditions
Alzheimer's Disease
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT05524571 | ACTIVE_NOT_RECRUITING | PHASE3
100 Participants

Study to Assess Batoclimab in Participants With Active Thyroid Eye Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-01-05
Completion: 2025-12-31
Conditions
Thyroid Eye Disease
Interventions
DRUG
No Results Yet
NCT05517421 | ACTIVE_NOT_RECRUITING | PHASE3
100 Participants

Study to Assess Batoclimab in Participants With Active Thyroid Eye Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2022-11-23
Completion: 2025-12-31
Conditions
Thyroid Eye Disease
Interventions
DRUG
No Results Yet
NCT05489705 | RECRUITING
1600 Participants

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-06
Start Date: 2022-08-16
Completion: 2029-08-17
Conditions
Obstructive Hypertrophic Cardiomyopathy
Interventions
DRUG
No Results Yet
NCT05481879 | RECRUITING | PHASE1/PHASE2
116 Participants

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2022-09-05
Completion: 2029-07-31
Conditions
Myotonic Dystrophy Type 1 (DM1)
Interventions
DRUG
No Results Yet
NCT05477563 | RECRUITING | PHASE3
26 Participants

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent ฮฒ-Thalassemia and Severe Sickle Cell Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2022-08-02
Completion: 2027-06-09
Conditions
Beta-Thalassemia Thalassemia Hematologic Diseases Genetic Diseases, Inborn Hemoglobinopathies Sickle Cell Disease Sickle Cell Anemia
Interventions
BIOLOGICAL
No Results Yet
NCT05474846 | RECRUITING | PHASE2/PHASE3
188 Participants

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2022-11-21
Completion: 2027-02-28
Conditions
Sleep Fatigue Anxiety Cancer Depression
Interventions
DRUG OTHER
No Results Yet
NCT05471921 | COMPLETED | NA
400 Participants

Effectiveness of an Evidence-based Stepped Care System for Alcohol and Other Drug Use Problems Among Congolese Refugees in Zambia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-04-26
Completion: 2025-02-24
Conditions
Alcohol and Substance-Related Mental Disorders
Interventions
BEHAVIORAL
NCT05469269 | RECRUITING | NA
800 Participants

Cleveland African American Prostate Cancer Project

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-06-09
Completion: 2026-02-28
Conditions
Prostate Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT05455684 | COMPLETED | PHASE3
513 Participants

A Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2022-06-22
Completion: 2024-09-18
Conditions
Depressive Disorder, Major Anhedonia
Interventions
DRUG OTHER
NCT05445466 | COMPLETED | NA
14 Participants

Causal Lesion Network Guided Treatment of Bipolar Mania With Transcranial Electrical Stimulation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2022-12-16
Completion: 2025-06-01
Conditions
Bipolar Disorder Schizo Affective Disorder
Interventions
DEVICE
NCT05443555 | RECRUITING | PHASE2
220 Participants

Gabapentin to Reduce Alcohol and Improve Viral Load Suppression

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-11-20
Completion: 2026-08-31
Conditions
HIV Heavy Drinking
Interventions
DRUG
No Results Yet
NCT05423912 | ACTIVE_NOT_RECRUITING | NA
29 Participants

Keeping on Course: A Communication-Focused Psychoeducational Program

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2023-02-08
Completion: 2025-12-05
Conditions
Mild Cognitive Impairment
Interventions
BEHAVIORAL
No Results Yet
NCT05422222 | RECRUITING | PHASE3
210 Participants

Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2022-06-21
Completion: 2030-06-30
Conditions
Cystic Fibrosis
Interventions
DRUG
No Results Yet
NCT05405660 | COMPLETED | PHASE2
196 Participants

A Study of CDX-0159 in Patients With Chronic Inducible Urticaria

Study Type: INTERVENTIONAL
Last Updated: 2025-11-06
Start Date: 2022-06-28
Completion: 2024-06-12
Conditions
Chronic Inducible Urticaria
Interventions
BIOLOGICAL DRUG
No Results Yet
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