Clinical Evaluation of Customized Attachment Composites in Clear Aligner Therapy

NCT ID: NCT07261735

Last Updated: 2025-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

24 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-08-25

Study Completion Date

2026-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This prospective observational clinical study aims to evaluate the three-dimensional surface wear and clinical survival of orthodontic attachments fabricated with customized composite materials used in clear aligner therapy. Attachments play a critical role in the biomechanical efficiency of aligner treatment by facilitating planned tooth movements. However, the mechanical and surface properties of the composites used for attachment fabrication may affect their wear behavior and long-term stability.

In this study, four different composite materials will be tested using a split-mouth design in patients treated with clear aligners. Each quadrant will receive a different composite, including both customized and universal types. All attachments will be fabricated using standardized digital templates and bonded under identical clinical conditions. Surface wear will be evaluated using three-dimensional optical scanning and metrology software at baseline, 1 week, 1 month, 3 months, and 6 months. Lost attachments will be replaced and recorded but excluded from wear analysis.

The results of this study are expected to provide valuable insights into the optimal material selection for clear aligner attachments, improving treatment accuracy and clinical durability.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The study is a prospective, observational, split-mouth clinical investigation conducted at the University of Health Sciences, Gülhane Faculty of Dentistry, Department of Orthodontics. It aims to compare the surface wear resistance and clinical performance of attachments fabricated with different composite resins used in clear aligner therapy.

Four composite materials will be evaluated: GC G-ænial A'Chord (control), Spectra ST HV, Spectra ST LV, and GC Aligner Connect. Each patient will receive four different materials applied to separate quadrants following a randomized split-mouth allocation. The study planning and randomization were performed by a single researcher to ensure methodological consistency. All attachments will be fabricated using standardized digital templates based on the virtual treatment plan. The bonding procedure will be carried out by one investigator using Transbond XT adhesive and 37% phosphoric acid etching for 15 seconds.

Intraoral scanning will be performed at baseline, 1 week, 1 month, 3 months, and 6 months. The scanned data will be analyzed using Zeiss Inspect software to quantify volumetric and surface wear. All 3D alignments and superimpositions will be performed by a blinded evaluator to ensure objectivity. Lost or fractured attachments will be recorded and replaced but excluded from quantitative wear analysis.

All participants will be followed for six months. Statistical analysis will include repeated-measures ANOVA and post-hoc testing with a significance level of p \< 0.05. Reliability will be evaluated using the intraclass correlation coefficient (ICC).

This study has been approved by the Gülhane Scientific Research Ethics Committee of the University of Health Sciences (Approval No: 2024/015, August 19, 2025). The findings are expected to enhance understanding of how different composite materials influence attachment wear and longevity in clear aligner therapy, thereby improving the accuracy and clinical predictability of treatment outcomes.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Clear Aligner Therapy - Attachment Wear and Bonding Performance

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group 1: All Participants

All participants receive four different composite materials using a randomized split-mouth design. Each quadrant is assigned one composite for attachment reproduction

GC G-ænial A'Chord Universal Composite

Intervention Type DEVICE

Universal composite resin used as the control material for attachment reproduction.

Spectra ST HV (High Viscosity)

Intervention Type DEVICE

High-viscosity universal composite resin clinically used for clear aligner attachment reproduction.

Spectra ST LV (Low Viscosity)

Intervention Type DEVICE

Low-viscosity universal composite resin clinically used for clear aligner attachment reproduction.

GC Aligner Connect Composite

Intervention Type DEVICE

Customized composite resin specifically developed for clear aligner attachments.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

GC G-ænial A'Chord Universal Composite

Universal composite resin used as the control material for attachment reproduction.

Intervention Type DEVICE

Spectra ST HV (High Viscosity)

High-viscosity universal composite resin clinically used for clear aligner attachment reproduction.

Intervention Type DEVICE

Spectra ST LV (Low Viscosity)

Low-viscosity universal composite resin clinically used for clear aligner attachment reproduction.

Intervention Type DEVICE

GC Aligner Connect Composite

Customized composite resin specifically developed for clear aligner attachments.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Fully erupted permanent dentition.
* No existing prosthetic restorations.
* Mild-to-moderate dental crowding or spacing (2-6 mm).
* Patients who are scheduled to undergo clear aligner therapy at the Department of Orthodontics, Gülhane Faculty of Dentistry, between 01.08.2025 and 01.08.2026.
* Patients who agree to participate and provide informed consent.

Exclusion Criteria

* History of previous fixed orthodontic treatment.
* Patients with poor predicted compliance or low cooperation.
* Presence of severe or generalized periodontal disease.
* High caries incidence or untreated caries.
* Poor oral hygiene
* Habitual consumption of hard foods.
* Bruxism
* Congenitally missing permanent teeth.
* Dental developmental anomalies.
* Teeth with existing composite resin restorations or ceramic crowns on buccal surfaces (which may interfere with attachment bonding or wear analysis)
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Saglik Bilimleri Universitesi

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Health Sciences, Gülhane Faculty of Dental Medicine

Ankara, , Turkey (Türkiye)

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Turkey (Türkiye)

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Gizem Boztaş Demir, Asst. Prof.

Role: CONTACT

+905331518464

Kübra Gülnur Topsakal, Assoc. Prof. Dr.

Role: CONTACT

+905369759013

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Gizem Demir, Assistant Professor

Role: primary

+905331518464

Kübra Gülnur Topsakal, Associate Professor

Role: backup

+905369759013

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

SBU-GULHANE-ORTHO-ATTACH-2025

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Split-Mouth Comparison of Invisalign Attachments
NCT07215598 NOT_YET_RECRUITING NA