HIIT Versus MICT in COPD: Effects on Oxygenation, Pulmonary Function, and Strength

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-01

Study Completion Date

2027-06-01

Brief Summary

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Chronic Obstructive Pulmonary Disease (COPD) is a progressive condition marked by airflow limitation and chronic inflammation, leading to reduced exercise capacity, peripheral muscle dysfunction, and dyspnea. High-Intensity Interval Training (HIIT) may offer a promising alternative for patients with low exercise tolerance; however, evidence on its effectiveness remains limited.

This study aims to compare the effects of HIIT and Moderate-Intensity Continuous Training (MICT) on muscle oxygenation, pulmonary function, exercise capacity, and peripheral muscle strength in individuals with COPD. Participants will undergo an 8-week exercise program, twice weekly. HIIT will consist of 1-minute intervals at 90% and 30-40% of peak workload, while MICT will involve continuous cycling at 65% of peak workload. Outcomes will be assessed at baseline, week 4, and week 8. Data will be analyzed using SPSS. This study seeks to determine the more effective training modality to optimize COPD rehabilitation.

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Detailed Description

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Conditions

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Chronic Obstructive Pulmonary Disease (COPD)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

HIIT or MICT will be applied in patients with COPD groups.

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Statistical Analyzer will be masked.

Study Groups

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Control Group

standard aerobic exercise will apply in moderate intensity continuous training.

Group Type ACTIVE_COMPARATOR

MICT

Intervention Type OTHER

Moderate intensity continous exercise

interval exercise group

Group Type EXPERIMENTAL

HIIT GROUP

Intervention Type OTHER

Participants will perform a 31-minute protocol on a cycle ergometer consisting of 1-minute high-intensity intervals at 90% of peak workload (W peak) and low-intensity intervals at 30-40% of W peak, twice a week for 8 weeks.

Interventions

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HIIT GROUP

Participants will perform a 31-minute protocol on a cycle ergometer consisting of 1-minute high-intensity intervals at 90% of peak workload (W peak) and low-intensity intervals at 30-40% of W peak, twice a week for 8 weeks.

Intervention Type OTHER

MICT

Moderate intensity continous exercise

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Diagnosed with Chronic Obstructive Pulmonary Disease (COPD),
* GOLD stage 2, 3, or 4,
* Willing to participate in the study,
* Aged between 40 and 80 years,
* Clinically stable (no significant deterioration in the current medical condition, no recent initiation of a new treatment, and no complications requiring hospitalization).

Exclusion Criteria

* Presence of visual, auditory, vestibular, cognitive, or neurological impairments that may affect balance,
* Any orthopedic, neurological, or cardiac conditions that may interfere with study participation or exercise,
* Presence of serious chronic diseases such as congestive heart failure, coronary artery disease, or chronic renal failure,
* Conditions that may cause physical limitations (e.g., limb amputation, significant musculoskeletal disorders, or postural abnormalities such as kyphosis or lordosis).

Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No