An Investigation of Different Type Single Limb Exercise Training Effects in Copd

NCT ID: NCT06471439

Last Updated: 2024-06-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-06-16

Study Completion Date

2025-01-02

Brief Summary

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COPD presents not only respiratory symtoms but also vascular or muscle dysfunction. Exercise limitation is observed in COPD. Especially, decreased exercise performance related to vascular and fatique in quadriceps muscle. Exercise training is important for aerobic performance increasing. Generally results show exercise training with both lower limb. Increaed arterial stiffness and fatigue are observed in COPD. One leg exercise training result is not enough to highlight these parameters.

Three types single leg exercise intervantion will be applied. Exercise capacity, muscle strength, lung function, electromyography, lactate and quality of life will be measured.

Detailed Description

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Three types single leg exercise intervantion will applied to COPD patients that devided three groups. One leg continuous exercise training will be aplied to one group. One leg HIIT exercise training will be aplied to other group. One leg resistance exercise training will be aplied to the last group.

Exercise capacity and muscle strength are assesed. Lung function is measured. Electormyography is recorded. Lactate and quality of life are measured.

Conditions

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Exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

three different type one leg exercise intervention are apllied in patients with copd
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Participants

Study Groups

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single leg resistance exercise intervantion in COPD

single leg resistance exercise intervantion in COPD will be perfomed at six weeks

Group Type ACTIVE_COMPARATOR

single leg exercise intervantion in COPD

Intervention Type OTHER

single leg exercise intervantions

1. high intensity interval training
2. continous exercise training
3. resistance exercise training

single leg continous exercise intervantion in COPD

single leg continous exercise intervantion in COPD will be perfomed at six weeks

Group Type ACTIVE_COMPARATOR

single leg exercise intervantion in COPD

Intervention Type OTHER

single leg exercise intervantions

1. high intensity interval training
2. continous exercise training
3. resistance exercise training

single leg high intensity exercise intervantion in COPD

single leg high intensity exercise intervantion in COPD will be perfomed at six weeks

Group Type ACTIVE_COMPARATOR

single leg exercise intervantion in COPD

Intervention Type OTHER

single leg exercise intervantions

1. high intensity interval training
2. continous exercise training
3. resistance exercise training

Interventions

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single leg exercise intervantion in COPD

single leg exercise intervantions

1. high intensity interval training
2. continous exercise training
3. resistance exercise training

Intervention Type OTHER

Other Intervention Names

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single leg exercise intervantion

Eligibility Criteria

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Inclusion Criteria

* COPD patients that applied to physiotherapy
* Cooperation for tests
* without severe ortopedical and neurological disease
* without severe cardiovascular disease
* To volunteer for the study.

Exclusion Criteria

* have an acute exacerbation or having exacerbation at last month
* hypoxemia (PaO2\<55mmHg)
* no cooperated to test without volunteer to study having ortophedical and neurological diesase that affecting of tests severe cardiovascular disease
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hacettepe University

OTHER

Sponsor Role lead

Responsible Party

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Elif Kocaaga

principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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elif kocaaga, ms

Role: PRINCIPAL_INVESTIGATOR

Hacettepe University

Locations

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Elif Kocaaga

Ankara, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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elif kocaaga, Ms

Role: CONTACT

+903123052525

elif kocaaga, Ms

Role: CONTACT

+903123052525

Facility Contacts

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elif kocaaga, Ms

Role: primary

+903123052525

References

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Dolmage TE, Goldstein RS. Effects of one-legged exercise training of patients with COPD. Chest. 2008 Feb;133(2):370-6. doi: 10.1378/chest.07-1423. Epub 2007 Oct 9.

Reference Type BACKGROUND
PMID: 17925417 (View on PubMed)

Evans RA, Dolmage TE, Mangovski-Alzamora S, Romano J, O'Brien L, Brooks D, Goldstein RS. One-Legged Cycle Training for Chronic Obstructive Pulmonary Disease. A Pragmatic Study of Implementation to Pulmonary Rehabilitation. Ann Am Thorac Soc. 2015 Oct;12(10):1490-7. doi: 10.1513/AnnalsATS.201504-231OC.

Reference Type BACKGROUND
PMID: 26291542 (View on PubMed)

MacInnis MJ, Morris N, Sonne MW, Zuniga AF, Keir PJ, Potvin JR, Gibala MJ. Physiological responses to incremental, interval, and continuous counterweighted single-leg and double-leg cycling at the same relative intensities. Eur J Appl Physiol. 2017 Jul;117(7):1423-1435. doi: 10.1007/s00421-017-3635-8. Epub 2017 May 11.

Reference Type BACKGROUND
PMID: 28497384 (View on PubMed)

Other Identifiers

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KA-22104

Identifier Type: -

Identifier Source: org_study_id

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