Effects of Chair-Based Exercise Training on Exercise Capacity in Patients With Acute Exacerbation of COPD

NCT ID: NCT05563493

Last Updated: 2024-02-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-08-20

Study Completion Date

2023-06-30

Brief Summary

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Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality worldwide, a respiratory disease characterized by chronic airflow limitation that is not completely reversible.

Impaired pulmonary functions, decreased exercise capacity and quality of life and increased dyspnea perception is prevalent in patients with acute exacerbations of COPD.It was demonstrated exercise training has beneficial effects in patients with acute exacerbations of COPD.

The purpose of this study to evaluate the effects of chair-based exercise training on exercise capacity, respiratory functions, dyspnea, balance, depression anxiety and quality of life in COPD patients in acute exacerbation.

Detailed Description

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Acute exacerbations of COPD are generally defined as events in the natural course of the disease characterized by a change in the patient's initial dyspnea, cough or sputum beyond normal daily variations. The main consequences of COPD in acute exacerbation are increased mortality, deterioration in health-related quality of life, faster decline in lung function, marked reduction in physical activity and worsening of peripheral muscle weakness, which have a direct impact on patients' health. Although exacerbations are diagnosed based on respiratory symptoms, there is evidence that they have systemic consequences, including a detrimental effect on skeletal muscle function, exercise tolerance and quality of life.

Chair-based exercise training is defined as a structured and progressive exercise program applied by trainers that provides stability using a chair, which is a part of exercise training for the elderly. It is thought that it would be beneficial to study such an exercise program, since COPD patients in acute exacerbation have less mobilization during hospitalization.

In a limited number of studies, some inconsistencies were observed in the exercises of patients with acute exacerbation of COPD. Studies can therefore now focus on investigating comparisons between different intervention lengths, session durations and frequencies, and intensities of exercise training. For this reason, in our planned study, we will investigate the effects of chair-based exercise training in COPD patients in acute exacerbation. There is no study in the literature investigating the effects of chair-based exercise training in COPD patients in acute exacerbation. For this reason, our study will provide important information support to the literature.

Conditions

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Acute Exacerbation of COPD

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Participants

Study Groups

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Treatment group, Chair-Based Exercise Training

Treatment group will receive chair-based exercise training. Chair-based exercise training consisting of 20 different exercises will be applied in 2-3 sets with an average of 8-15 repetitions. Rest between sets will average 45-60 seconds.

Group Type EXPERIMENTAL

Treatment group, Chair-Based Exercise Training

Intervention Type OTHER

The weights of the elastic bands to be used in the exercises will be determined by the physiotherapist according to the abilities and development of the participants.

The intensity of the exercise will be adjusted according to the dyspnea or fatigue patients feel according to the Modified Borg Scale.

During the exercises, heart rate and oxygen saturation will be measured with a pulse oximeter, and blood pressure will be measured with a sphygmomanometer.

Chair-based exercise training will be applied to the patients every day they are hospitalized.

Control group, Breathing exercise

Control group will receive breathing exercises.

Group Type OTHER

Control group, Breathing exercise

Intervention Type OTHER

Breathing exercise will be applied to the patients every day they are hospitalized.

Interventions

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Treatment group, Chair-Based Exercise Training

The weights of the elastic bands to be used in the exercises will be determined by the physiotherapist according to the abilities and development of the participants.

The intensity of the exercise will be adjusted according to the dyspnea or fatigue patients feel according to the Modified Borg Scale.

During the exercises, heart rate and oxygen saturation will be measured with a pulse oximeter, and blood pressure will be measured with a sphygmomanometer.

Chair-based exercise training will be applied to the patients every day they are hospitalized.

Intervention Type OTHER

Control group, Breathing exercise

Breathing exercise will be applied to the patients every day they are hospitalized.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients who were hospitalized due to acute exacerbation of COPD

Exclusion Criteria

* Patients with orthopedic or neurological problems that may interfere with assessment and education,
* Uncooperative patients,
* Patients with advanced heart problems such as acute coronary syndrome, stable angina pectoris, severe arrhythmias (Atrial fibrillation etc.), decompensated heart failure.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Necmettin Erbakan University

OTHER

Sponsor Role lead

Responsible Party

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Zeynep Pelin Dündar

Research Assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Zeynep Pelin DÜNDAR, MSc,PT

Role: PRINCIPAL_INVESTIGATOR

Necmettin Erbakan University

Nihan KAFA

Role: STUDY_DIRECTOR

Gazi University

Hülya VATANSEV

Role: STUDY_DIRECTOR

Necmettin Erbakan University

Neslihan DURUTÜRK

Role: STUDY_CHAIR

Baskent University

Adil ZAMANİ

Role: STUDY_CHAIR

Necmettin Erbakan University

Locations

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Necmettin Erbakan University Nezahat Keleşoğlu Faculty of Health Sciences

Konya, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Liao S, Wang F, Lin Q, Jian F, Li Y, Zhong Q, Huang Y, Lin Y, Wang H. Effect of sitting and lying Liuzijue exercise for pulmonary rehabilitation in acute exacerbation of chronic obstructive pulmonary disease patients with non-invasive ventilation: a randomized controlled trial. Ann Palliat Med. 2021 Sep;10(9):9914-9926. doi: 10.21037/apm-21-2157.

Reference Type BACKGROUND
PMID: 34628916 (View on PubMed)

Knaut C, Bonfanti Mesquita C, Dourado VZ, de Godoy I, Tanni SE. Evaluation of Inflammatory Markers in Patients Undergoing a Short-Term Aerobic Exercise Program while Hospitalized due to Acute Exacerbation of COPD. Int J Inflam. 2020 Apr 28;2020:6492720. doi: 10.1155/2020/6492720. eCollection 2020.

Reference Type BACKGROUND
PMID: 32411343 (View on PubMed)

Burtin C, Decramer M, Gosselink R, Janssens W, Troosters T. Rehabilitation and acute exacerbations. Eur Respir J. 2011 Sep;38(3):702-12. doi: 10.1183/09031936.00079111. Epub 2011 Jun 30.

Reference Type BACKGROUND
PMID: 21719481 (View on PubMed)

Kon SS, Canavan JL, Man WD. Pulmonary rehabilitation and acute exacerbations of COPD. Expert Rev Respir Med. 2012 Nov;6(5):523-31; quiz 531. doi: 10.1586/ers.12.47.

Reference Type BACKGROUND
PMID: 23134247 (View on PubMed)

Other Identifiers

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1

Identifier Type: -

Identifier Source: org_study_id

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