Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
60 participants
OBSERVATIONAL
2024-12-10
2026-03-30
Brief Summary
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Detailed Description
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Severe chronic generalized periodontitis may result in systemic inflammation and endothelial dysfunction. Periodontal bacteria produce endotoxins in the form of lipopolysaccharide (LPS). Circulating LPS causes an early systemic inflammatory response in the intima.
The aim of this study is to assess the relationship between bacteria in atheroma plaque, and dental plaque in patients grouped using the new periodontal classification. In addition, the relationship between demographic findings and bacterial count and frequency will be evaluated.
Conditions
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Study Design
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OTHER
CROSS_SECTIONAL
Study Groups
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Patients diagnosed with endarterectomy
atheroma plaque
During the endarterectomy procedure, samples will be collected for study from some of the atheroma plaques routinely taken for pathology from patients.
dental plaque
Subgingival plaque samples will be collected from patients before the endarterectomy procedure.
Interventions
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atheroma plaque
During the endarterectomy procedure, samples will be collected for study from some of the atheroma plaques routinely taken for pathology from patients.
dental plaque
Subgingival plaque samples will be collected from patients before the endarterectomy procedure.
Eligibility Criteria
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Inclusion Criteria
* Not receiving chemotherapy
* Not having received this treatment before
Exclusion Criteria
* Patients with severe heart disease
18 Years
85 Years
ALL
No
Sponsors
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Istanbul Saglik Bilimleri University
OTHER
Responsible Party
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Ayşe Toraman
associate professor
Locations
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Health Sciences University, Hamidiye Faculty of Dentistry, Department of Periodontology
Istanbul, , Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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1417
Identifier Type: -
Identifier Source: org_study_id
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