Polymorphonuclear Cells' Sensitivity to Aggregatibacter Actinomycetemcomitans Bacteria in Patients With Aggressive Periodontitis
NCT ID: NCT02010307
Last Updated: 2013-12-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
75 participants
INTERVENTIONAL
2014-01-31
2015-10-31
Brief Summary
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a specific bacteria: Aggregatibacter actinomycetemcomitans (Aa) is associated with this disease, and found to damage leukocytes by using a specific leukotoxin.
in the research the investigators are aiming to find molecular and immunological basis to aggressive periodontitis.
Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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aggressive periodontitis
25 patients with aggressive periodontitis blood extraction
blood extraction
6 ml blood extraction from each patients in all 3 arms of the study
chronic periodontitis
25 patients with chronic periodontitis blood extraction
blood extraction
6 ml blood extraction from each patients in all 3 arms of the study
healthy
25 healthy periodontal patients blood extraction
blood extraction
6 ml blood extraction from each patients in all 3 arms of the study
Interventions
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blood extraction
6 ml blood extraction from each patients in all 3 arms of the study
Eligibility Criteria
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Inclusion Criteria
* healthy
* diagnosed with chronic/aggressive periodontal disease
* interested in participating the research
Exclusion Criteria
* using alcohol, or drugs
* pregnancy
18 Years
50 Years
ALL
Yes
Sponsors
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Polak David
OTHER
Responsible Party
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Polak David
senior dentist, periodontology department
Principal Investigators
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David Polak, DMD, PhD
Role: PRINCIPAL_INVESTIGATOR
Haddasah Medical Center
Locations
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Hadassah Medical Organization, Jerusalem, Israel
Jerusalem, , Israel
Countries
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Central Contacts
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Other Identifiers
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davidp-HMO-CTIL
Identifier Type: -
Identifier Source: org_study_id