Assessment of Response to the Conventional Periodontal Treatment Based on the Blood Group Phenotypes.
NCT ID: NCT03644901
Last Updated: 2019-03-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
60 participants
OBSERVATIONAL
2018-01-15
2019-03-10
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Patients whose blood type is A
Applying nonsurgical periodontal treatment (scaling and root planning).
nonsurgical periodontal treatment
patients will undergo nonsurgical periodontal treatment to reduce the relative attachment level and improve the probing depth. An initial session will be conducted to remove supra gingival plaque and calculus. another appointment is set to perform full moth scalling and root planing.
Patients whose blood type is B
Applying nonsurgical periodontal treatment (scaling and root planning).
nonsurgical periodontal treatment
patients will undergo nonsurgical periodontal treatment to reduce the relative attachment level and improve the probing depth. An initial session will be conducted to remove supra gingival plaque and calculus. another appointment is set to perform full moth scalling and root planing.
Patients whose blood type is AB
Applying nonsurgical periodontal treatment (scaling and root planning).
nonsurgical periodontal treatment
patients will undergo nonsurgical periodontal treatment to reduce the relative attachment level and improve the probing depth. An initial session will be conducted to remove supra gingival plaque and calculus. another appointment is set to perform full moth scalling and root planing.
Patients whose blood type is O
Applying nonsurgical periodontal treatment (scaling and root planning).
nonsurgical periodontal treatment
patients will undergo nonsurgical periodontal treatment to reduce the relative attachment level and improve the probing depth. An initial session will be conducted to remove supra gingival plaque and calculus. another appointment is set to perform full moth scalling and root planing.
Interventions
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nonsurgical periodontal treatment
patients will undergo nonsurgical periodontal treatment to reduce the relative attachment level and improve the probing depth. An initial session will be conducted to remove supra gingival plaque and calculus. another appointment is set to perform full moth scalling and root planing.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* have at least 20 teeth excluding the third molars.
* had not received any periodontal treatment or antibiotic therapy for dental or medical reason 6 month prior to the study.
* diagnosed with generalized chronic periodontitis (\>30% of the sites have probing depth ≥4), and a minimum of six teeth with probing depth of 5-6 mm.
Exclusion Criteria
* pregnancy.
* history of a systematic disease such as diabetes, leukemia, epilepsy.
* participants who are unable to perform routine oral hygiene.
* use of orthodontic appliances.
* participants who are unable to perform routine oral hygiene.
20 Years
60 Years
ALL
No
Sponsors
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Damascus University
OTHER
Responsible Party
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Principal Investigators
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Mohammad Ammar Kouky, DDS MSc
Role: PRINCIPAL_INVESTIGATOR
PhD Student in Periododontics, University of Damascus Dental School, Damascus
Mohammad Monzer Alsabbagh, DDS MSc PhD
Role: STUDY_CHAIR
Associate Professor of Periodontics, University of Damascus Dental School, Damascus, Syria
Locations
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Department of Periodontics
Damascus, , Syria
Countries
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References
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Pai GP, Dayakar MM, Shaila M, Dayakar A. Correlation between "ABO" blood group phenotypes and periodontal disease: Prevalence in south Kanara district, Karnataka state, India. J Indian Soc Periodontol. 2012 Oct;16(4):519-23. doi: 10.4103/0972-124X.106892.
Demir T, Tezel A, Orbak R, Eltas A, Kara C, Kavrut F. The Effect of ABO Blood Types on Periodontal Status. Eur J Dent. 2007 Jul;1(3):139-43.
Gautam A, Mittal N, Singh TB, Srivastava R, Verma PK. Correlation of ABO Blood Group Phenotype and Rhesus Factor with Periodontal Disease: An Observational Study. Contemp Clin Dent. 2017 Apr-Jun;8(2):253-258. doi: 10.4103/ccd.ccd_307_17.
Wang W, Liu L, Wang Z, Wei M, He Q, Ling T, Cao Z, Zhang Y, Wang Q, Shi M. Impact of ABO blood group on the prognosis of patients undergoing surgery for esophageal cancer. BMC Surg. 2015 Sep 29;15:106. doi: 10.1186/s12893-015-0094-1.
Yu Q, Wang L, Zhang S, Feng T, Li L, Chen B, Chen M. The role of ABO blood groups in Crohn's disease and in monitoring response to infliximab treatment. Blood Transfus. 2016 Sep;14(5):460-4. doi: 10.2450/2016.0199-15. Epub 2016 Feb 24.
Other Identifiers
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UDDS-Perio-03-2018
Identifier Type: -
Identifier Source: org_study_id
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