Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Periodontitis.
NCT ID: NCT05906797
Last Updated: 2023-12-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
60 participants
INTERVENTIONAL
2020-09-07
2023-12-12
Brief Summary
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Detailed Description
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60 patients: 30 with periodontitis and 30 with healthy controls and without periodontitis history.
All the patients are assessed for clinical, periodontal, blood and non-invasive ultrasound cardiovascular parameters. Measurements are taken before and after initial periodontal treatment in the periodontal subjects.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Periodontitis
Subjects diagnosed with periodontitis according to the most recent international guidelines and without cardiovascular diseases.
Non-surgical periodontal treatment
Subgingival biofilm ultrasonic debridement
Healthy
Subjects without periodontitis and with good gingival health.
No interventions assigned to this group
Interventions
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Non-surgical periodontal treatment
Subgingival biofilm ultrasonic debridement
Eligibility Criteria
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Inclusion Criteria
* Clinically diagnosed with healthy periodontum withouth periodontitis history according to the EFP/AAP 2017 criteria.
Exclusion Criteria
* Pregnancy.
* Cardiovascular Diseases.
HEALTHY GROUP
* Scaling, antibiotics, NSAIDs, immunosuppressants during the last 6 months.
* Pregnancy.
* Cardiovascular Diseases.
ALL
Yes
Sponsors
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University of Catania
OTHER
Responsible Party
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Gaetano Isola
Researcher
Locations
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AOU Policlinico G. Rodolico
Catania, , Italy
Countries
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Other Identifiers
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121-22
Identifier Type: -
Identifier Source: org_study_id