Effect of Periodontal Therapy in the Systemic Status of Individuals With Chronic Periodontitis and Diabetes Type 2

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-11-30

Study Completion Date

2020-08-31

Brief Summary

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This study will evaluate if periodontal mechanical treatment is capable to alter immunological and genetical parameters related to systemic health in patients with chronic periodontitis ant diabetes type 2.

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Detailed Description

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Conditions

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Chronic Periodontitis Diabetes Type 2

Study Groups

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root planning

Mechanical periodontal therapy

Intervention Type DEVICE

nonsurgical periodontal therapy

Intervention Type PROCEDURE

Interventions

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Mechanical periodontal therapy

Intervention Type DEVICE

nonsurgical periodontal therapy

Intervention Type PROCEDURE

Other Intervention Names

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periodontal debridment

Eligibility Criteria

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Inclusion Criteria

Periodontitis group:

* Minimum of 15 teeh;
* At least 30% of sites with periodontal probing depth ≥ 4 mm and at least two teeth with CAL ≥ 3 mm; Age ≥30 years;

Control group:

* Systemically healthy;
* 20 teeth;
* Probing depth ≤3 mm, clinical attachment level ≤3 mm , ≤10% of sites with bleeding on probing.

Exclusion Criteria

* Periodontal treatment in the last six months;
* Continued use of medications such as antibiotics, immunomodulatory, anti-inflammatory drugs or corticosteroids in the last three months;
* Systemic diseases that interfere with periodontal condition, except for diabetes for the test group (HIV, cancer, immune disorders, acute infections, severe allergies, gastrointestinal or kidney disease, morbid obesity \[BMI 40 kg / m2\] or underweight \[evil nourished BMI \<18.5 kg / m2\], etc.); Pregnant or lactating; smoking; Age \<30 years; Indigenous groups.

Minimum Eligible Age

30 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes