Effect of Non Surgical Treatment of Periodontitis on Diabetes Control

NCT ID: NCT02745015

Last Updated: 2016-07-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-12-31

Study Completion Date

2015-05-31

Brief Summary

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The aim of this study is to investigate the effects of non-surgical periodontal treatment on the metabolic control of type2 diabetes patients. Patients with type two diabetes mellitus patients and confirmed chronic periodontitis will be selected and randomly assign to two groups. The treatment group will receive immediate full-mouth scaling and root planing whereas the control group will be scheduled to receive periodontal treatment at the following 3-month visit. Plaque index, bleeding index, probing pocket depth, recessions and cervical attachment loss will be recorded at baseline, at six weeks and at three months. Glycated haemoglobin (HbA1c) and C-reactive protein (CRP) will be analysed at baseline and three months following enrolment.

Detailed Description

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The aim of this study is to investigate the effects of non-surgical periodontal treatment on the metabolic control of type2 diabetes patients. Patients with type two diabetes mellitus patients and confirmed chronic periodontitis will be selected and randomly assign to two groups. The treatment group will receive immediate full-mouth scaling and root planing whereas the control group will be scheduled to receive periodontal treatment at the following 3-month visit. Plaque index, bleeding index, probing pocket depth, recessions and cervical attachment loss will be recorded at baseline, at six weeks and at three months. Glycated haemoglobin (HbA1c) and C-reactive protein (CRP) will be analysed at baseline and three months following enrolment.

Conditions

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Periodontitis Diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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treatment

immediate non-surgical periodontal treatment

Group Type EXPERIMENTAL

non-surgical periodontal treatment

Intervention Type PROCEDURE

full-mouth scaling and root planing

control

non-surgical periodontal treatment scheduled for the following 3-monthly visit

Group Type OTHER

non-surgical periodontal treatment

Intervention Type PROCEDURE

full-mouth scaling and root planing

Interventions

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non-surgical periodontal treatment

full-mouth scaling and root planing

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Type 2 diabetes for at least one year
* periodontitis
* HbA1c \> 7%

Exclusion Criteria

* Periodontal treatment in the last 6 months
* antibiotics in the last 3 months
* tobacco smoking
* pregnancy
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yaounde Central Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Sobngwi Eugene

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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National Obesity Centre

Yaoundé, , Cameroon

Site Status

Countries

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Cameroon

References

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Tsobgny-Tsague NF, Lontchi-Yimagou E, Nana ARN, Tankeu AT, Katte JC, Dehayem MY, Bengondo CM, Sobngwi E. Effects of nonsurgical periodontal treatment on glycated haemoglobin on type 2 diabetes patients (PARODIA 1 study): a randomized controlled trial in a sub-Saharan Africa population. BMC Oral Health. 2018 Feb 26;18(1):28. doi: 10.1186/s12903-018-0479-5.

Reference Type DERIVED
PMID: 29482543 (View on PubMed)

Other Identifiers

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CNO20154

Identifier Type: -

Identifier Source: org_study_id

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