Non-surgical Periodontal Therapy Effects Metabolic Control in Diabetics

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-06-30

Study Completion Date

2008-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to determine whether nonsurgical periodontal therapy is effective in the metabolic control of patients with type II Diabetes mellitus.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Glycemic Control in T2DM Through Non-Surgical Periodontal Therapy

NCT03343366

Chronic Periodontitis Type 2 Diabetes Mellitus

COMPLETED PHASE2/PHASE3

Periodontal Treatment and Glycemic Control

NCT01901926

Diabetes Mellitus Type 2

UNKNOWN NA

Type I Diabetes and Non-surgical Periodontal Treatment

NCT05569525

Type 1 Diabetes Periodontitis Periodontal Diseases +3 more

ACTIVE_NOT_RECRUITING NA

Effect of Non-surgical Periodontal Treatment on HbA1c in Type 2 Diabetic Patients

NCT02652026

Chronic Periodontitis Type 2 Diabetes Mellitus

COMPLETED NA

Periodontal Treatment and Metabolic Control in Type 2 Diabetic Patients

NCT01291875

Type 2 Diabetes Mellitus Periodontal Disease

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Type 2 diabetes mellitus (DM2), the most common type of diabetes, is characterized by hyperglycemia, hyperlipidemia, and associated complications. The classic major complications of diabetes are microangiopathy, nephropathy, neuropathy, macrovascular disease, delayed wound healing, and periodontitis. There is an interacting, complex relationship between diabetes and periodontitis.Many studies have shown a greater incidence and a greater severity of periodontitis in diabetic patients.Meanwhile, a number of studies have suggested that periodontitis may actually be a risk factor for diabetic complications as well. This study is performed to investigate the effects of non-surgical periodontal therapy on metabolic control in DM2 patients.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Metabolic Control

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Scalig and Rootplaning

patients will receive scaling and root planing therapy

Group Type ACTIVE_COMPARATOR

Scaling and Rootplaning

Intervention Type PROCEDURE

All patients in the test group receive scaling and rootplaning under local anesthesia

control

patients in control group will not receive periodontal treatment in the time period of the study

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Scaling and Rootplaning

All patients in the test group receive scaling and rootplaning under local anesthesia

Intervention Type PROCEDURE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

test group control group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

(1) mild to moderate periodontitis according to the criteria of the American Academy of Periodontology (32); (2) diagnosis of DM2 with glycated hemoglobin (HbA1c) values over 7%; (3) no major diabetic complications; (4) blood sugar controlled with glybenclamide and metformin, without insulin administration; and (5) no systemic antibiotic administration or periodontal treatment within the last 6 months.

Exclusion Criteria

(1) presence of systemic diseases other than DM2 that may influence the course of periodontal disease; (2) intake of immunosuppressive drugs, steroids, hydantoin, or non-steroidal anti-inflammatory drugs; (3) tobacco use; (4) pregnancy or intention to become pregnant during the study period; (5) fixed orthodontic appliances; and (5) refusal or inability to give informed consent

Minimum Eligible Age

30 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No