Immunoregulation of Periodontal Disease

NCT ID: NCT00702429

Last Updated: 2014-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

23 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-08-31

Study Completion Date

2010-07-31

Brief Summary

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Our design is to test in hospital practice a selection of immune parameters that could assess the pathophysiology and progression of periodontal lesions.

Detailed Description

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These parameters will be measured in 25 healthy volunteers and 25 moderate-to severe periodontal disese patients. Phagocytes will be tested phenotypically and functionally, both ex vivo and in vitro.

Conditions

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Periodontal Disease

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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1

Patients achieve of parodontopathies

Group Type EXPERIMENTAL

Blood sampling

Intervention Type OTHER

Analysis of the PNN, analysis of the monocytes

2

Patients without parodontales diseases

Group Type PLACEBO_COMPARATOR

Blood sampling

Intervention Type OTHER

Analysis of the PNN, analysis of the monocytes

Interventions

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Blood sampling

Analysis of the PNN, analysis of the monocytes

Intervention Type OTHER

Blood sampling

Analysis of the PNN, analysis of the monocytes

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Persons appearing spontaneously at the consultation of parodontologie for parodontale disease,
* persons agreeing to undergo a sampling of blood intended for the search

Exclusion Criteria

* Presence of a chronic or pointed pathology,
* an age 18-year-old subordinate or 65-year-old superior,
* pregnant women,
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Assistance Publique Hopitaux De Marseille

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Joana VITTE, MD

Role: PRINCIPAL_INVESTIGATOR

Assistance Publique des Hôpitaux de Marseille

Locations

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Hopital de la Conception- Laboratoire d'Immunologie

Marseille, , France

Site Status

Countries

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France

Other Identifiers

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2007-A00632-51

Identifier Type: -

Identifier Source: org_study_id

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