Active Matrix Metalloproteinase-8 (aMMP-8) Chair-side Test in Different Periodontal Disease
NCT ID: NCT03527901
Last Updated: 2018-05-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
103 participants
OBSERVATIONAL
2015-03-01
2016-06-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
CROSS_SECTIONAL
Study Groups
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Chronic periodontitis
This groups participant has radiographically moderate alveolar bone loss, CAL \> 5 mm and PD \>6 mm in several sites of each quadrant
GCF collection with aMMP-8 chair side test
Saliva collection
Generalized aggressive periodontitis
This demonstrated a generalized pattern of severe breakdown and CAL \> 5 mm and PD \> 6 mm on 8 \> teeth; minimum three of those were other than first incisors or first molars
GCF collection with aMMP-8 chair side test
Saliva collection
Gingivitis
This group has varying degrees of gingival inflammation, with CAL \< 2 mm, without any radiographical bone loss due to periodontitis
GCF collection with aMMP-8 chair side test
Saliva collection
Implant
Implants classified PD \< 5 mm, no bleeding on probing, no suppuration and no radiographic bone loss \> 0.5 mm
GCF collection with aMMP-8 chair side test
Saliva collection
Health
Probing depth (PD) \< 3mm, no gingival recession due to periodontal disease, and clinical attachment level (CAL) \< 2 mm, BOP in \< 10% of full-mouth score examination
GCF collection with aMMP-8 chair side test
Saliva collection
Interventions
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GCF collection with aMMP-8 chair side test
Saliva collection
Eligibility Criteria
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Inclusion Criteria
* Nonsmokers
Exclusion Criteria
* Participants who took regular medications that could affect of periodontal tissue
* Participants who received antibiotics less than 10 weeks before the study
20 Years
60 Years
ALL
No
Sponsors
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Aydin Adnan Menderes University
OTHER
Responsible Party
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Veli Özgen Öztürk
Principal Investigator
Other Identifiers
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BAP-17/1
Identifier Type: -
Identifier Source: org_study_id
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