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Gingivitis and Periodontitis as a Risk Factor for Stroke

NCT ID: NCT05101434

Last Updated: 2021-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-10

Study Completion Date

2021-07-20

Brief Summary

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Periodontitis and gingivitis are one of the most infectious diseases in humans. Several studies have been carried out on the dependence of periodontitis and stroke. The aim of this study was to investigate gingivitis and periodontitis as risk factors for stroke in the Pakistani population.

Detailed Description

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Epidemiologic studies have shown that cerebrovascular accident (CVA) is the 3rd cause of death in developed countries with 0.8 % prevalence in the whole population. Although, the prevalence rate of stroke is reduced yet is one of the most important health problems in the United State. Periodontitis and gingivitis are the two most infectious man diseases. Today, it is estimated that about 35% of people over 30-year-old in America and 50-55% of people in developing countries are involved with these diseases.

These diseases are due to the practice of chronic bacterial infection and the inflammatory response of the host. The relationship between periodontitis and CVA was first introduced by Mackenzi and Millard in 1963 but the importance of this issue was not understood. Periodontal infection can be a complex multiphase disease by associating this infection with organ systems such as cardiovascular, endocrine, reproductive, and respiratory systems. Nowadays, periodontitis is considered a risk factor for atherosclerosis and thromboembolic disease.

Conditions

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Gingivitis Periodontitis Stroke

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Periodontal Probing

with the help Michigan probe, periodontal pocket measurement was done.

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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ROAG revised oral assessment guide Community periodontal index Gingival Index

Eligibility Criteria

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Inclusion Criteria

* Diagnosed stroke by using brain imaging from magnetic resonance imaging and/or computerized tomography.

Exclusion Criteria

* Not willing to participate
* Neurological complications other than stroke
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shaheed Zulfiqar Ali Bhutto Medical University

OTHER

Sponsor Role lead

Responsible Party

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Muhammad Hassan

Registrar Neurology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Muhammad Hassan, MD

Role: PRINCIPAL_INVESTIGATOR

Shaheed Zulfiqar Ali Bhutto Medical University

Locations

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Shaheed Zulfiqar Ali Bhutto Medical University

Islamabad, Capital, Pakistan

Site Status

Countries

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Pakistan

Other Identifiers

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Gingivitis and Stroke

Identifier Type: -

Identifier Source: org_study_id