The Effect of Breathing on Cognitive Performance and Stress
NCT ID: NCT06986135
Last Updated: 2025-05-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
66 participants
INTERVENTIONAL
2024-08-01
2025-05-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
OTHER
SINGLE
Study Groups
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Box Breathing group
Group to be assigned box breathing.
Box Breathing
Box breathing consisted of a 4 second inhale, 4 second hold, 4 second exhale, 4 second hold; for 4 minutes.
Prolonged Exhalation Breathing assignment group
Breathing group to be assigned the prolonged exhalation intervention.
Prolonged Exhalation
Prolonged Exhalation consisted of a deep, 3 second inhale, followed by a slow 6 second exhale through pursed lips, once every 30 seconds for 4 minutes.
Placebo (normal breathing) group
This group is not assigned a breathing technique, and acts as a placebo.
Normal Breathing
This was the placebo, normal breathing group was instructed to breath as they normally would for the entirety of the 4 minute period.
Interventions
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Box Breathing
Box breathing consisted of a 4 second inhale, 4 second hold, 4 second exhale, 4 second hold; for 4 minutes.
Prolonged Exhalation
Prolonged Exhalation consisted of a deep, 3 second inhale, followed by a slow 6 second exhale through pursed lips, once every 30 seconds for 4 minutes.
Normal Breathing
This was the placebo, normal breathing group was instructed to breath as they normally would for the entirety of the 4 minute period.
Eligibility Criteria
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Inclusion Criteria
* Between the ages of 18-39,
* Student at Texas State.
Exclusion Criteria
* Consuming any medication for psychiatric disorders (i.e., anxiety, depression, ADHD)
* Being diagnosed with any psychiatric or physical conditions
* Any major stressors in the last 30 days (i.e., birth of a child, abortion, divorce).
18 Years
39 Years
ALL
Yes
Sponsors
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Texas State University, San Marcos
OTHER
Texas State University
OTHER
Responsible Party
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Matt McAllister
Associate Professor
Locations
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Texas State University, Metabolic & Applied Physiology Lab
San Marcos, Texas, United States
Countries
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References
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Kotlyar M, Donahue C, Thuras P, Kushner MG, O'Gorman N, Smith EA, Adson DE. Physiological response to a speech stressor presented in a virtual reality environment. Psychophysiology. 2008 Nov;45(6):1034-7. doi: 10.1111/j.1469-8986.2008.00690.x. Epub 2008 Sep 4.
Allen AP, Kennedy PJ, Dockray S, Cryan JF, Dinan TG, Clarke G. The Trier Social Stress Test: Principles and practice. Neurobiol Stress. 2016 Nov 12;6:113-126. doi: 10.1016/j.ynstr.2016.11.001. eCollection 2017 Feb.
Matsumoto T, Masuda T, Hotta K, Shimizu R, Ishii A, Kutsuna T, Yamamoto K, Hara M, Takahira N, Matsunaga A. Effects of prolonged expiration breathing on cardiopulmonary responses during incremental exercise. Respir Physiol Neurobiol. 2011 Sep 15;178(2):275-82. doi: 10.1016/j.resp.2011.06.025. Epub 2011 Jul 7.
Narkiewicz K, van de Borne P, Montano N, Hering D, Kara T, Somers VK. Sympathetic neural outflow and chemoreflex sensitivity are related to spontaneous breathing rate in normal men. Hypertension. 2006 Jan;47(1):51-5. doi: 10.1161/01.HYP.0000197613.47649.02. Epub 2005 Dec 12.
Ntovas P, Loumprinis N, Maniatakos P, Margaritidi L, Rahiotis C. The Effects of Physical Exercise on Saliva Composition: A Comprehensive Review. Dent J (Basel). 2022 Jan 5;10(1):7. doi: 10.3390/dj10010007.
Dillard CC, Martaindale H, Hunter SD, McAllister MJ. Slow Breathing Reduces Biomarkers of Stress in Response to a Virtual Reality Active Shooter Training Drill. Healthcare (Basel). 2023 Aug 21;11(16):2351. doi: 10.3390/healthcare11162351.
Kim HG, Cheon EJ, Bai DS, Lee YH, Koo BH. Stress and Heart Rate Variability: A Meta-Analysis and Review of the Literature. Psychiatry Investig. 2018 Mar;15(3):235-245. doi: 10.30773/pi.2017.08.17. Epub 2018 Feb 28.
Other Identifiers
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IRB #9665
Identifier Type: -
Identifier Source: org_study_id
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