The Proposed Study Aims to Investigate the Efficacy of Quercetin as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis
NCT ID: NCT06982248
Last Updated: 2025-05-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
PHASE2
60 participants
INTERVENTIONAL
2024-08-15
2025-06-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
Group 2: Periodontitis patients treated by NSPT and chitosan nanoparticles gel. Group 3: Periodontitis patients treated by NSPT only. Group 4: Periodontally healthy subjects.
TREATMENT
SINGLE
Study Groups
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Group 1: Periodontitis patients treated by NSPT and chitosan nanoparticles gel loaded by quercetin
selected patients receive SRP and chitosan nanoparticles gel loaded by quercetin
NSP and chitosan nanoparticles gel loaded by quercetin
NSP and chitosan nanoparticles gel loaded by quercetin
Group 2: Periodontitis patients treated by NSPT and chitosan nanoparticles gel.
selected patients receive SRP and chitosan nanoparticles gel
NSP and chitosan nanoparticles gel
NSP and chitosan nanoparticles gel
Group 3: Periodontitis patients treated by NSPT only
NSPT
scaling and root planning
NSPT
Group 4: Periodontally healthy subjects.
healthy individual act as control group
No interventions assigned to this group
Interventions
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NSP and chitosan nanoparticles gel loaded by quercetin
NSP and chitosan nanoparticles gel loaded by quercetin
NSP and chitosan nanoparticles gel
NSP and chitosan nanoparticles gel
scaling and root planning
NSPT
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Thyroid disease
* Patients with sensitivity to the medication used in the study
* patients with a history of antibiotic use or anti-inflammatory drugs during the previous 3 months prior to the study will be excluded from the study.
* Additionally, patients with systemic diseases, smokers, pregnant and lactating patients, and patients not compliant with oral hygiene procedures will also be excluded
25 Years
55 Years
ALL
Yes
Sponsors
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Mansoura University
OTHER
Responsible Party
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Principal Investigators
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Jilan mohamed
Role: STUDY_DIRECTOR
Mansoura University
Locations
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Faculty of Dentistry, Mansoura University
Aga, , Egypt
Countries
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Other Identifiers
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A03030240H
Identifier Type: -
Identifier Source: org_study_id
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