The Use of Chlorhexidine and a Probiotic Lozenge in the Nonsurgical Therapy of Periodontitis
NCT ID: NCT05548361
Last Updated: 2025-06-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
90 participants
INTERVENTIONAL
2022-04-01
2024-12-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Active Chx
This group will receive active chlorhexidine and placebo probiotics
active chlorhexidine and placebo probiotic
the randomized patients will be receive active chlorhexidine rinse and placebo probiotic
Active probiotics
This group will receive placeo chlorhexidine and active probiotics
placebo chlorhexidine and active probiotic
the randomized patients will receive placebo chlorhexidine rinse and active probiotic
Active Chx & probiotics
This group will receive active chlorhexidine and active probiotics
active chlorhexidine and active probiotic
the randomized patients will receive active chlorhexidine rinse and active probiotic
Interventions
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active chlorhexidine and placebo probiotic
the randomized patients will be receive active chlorhexidine rinse and placebo probiotic
placebo chlorhexidine and active probiotic
the randomized patients will receive placebo chlorhexidine rinse and active probiotic
active chlorhexidine and active probiotic
the randomized patients will receive active chlorhexidine rinse and active probiotic
Eligibility Criteria
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Inclusion Criteria
* A minimum of three natural teeth in each quadrant, excluding third molars
* Willing and able to give informed consent
* Not more than 50% of the patients in each group will be smokers.
* Smokers should smoke between 10 to 40 cigarettes a day
Exclusion Criteria
* Patients with orthodontic appliances (removable or fixed)
* Pregnant or lactating woman
* Patients with a history of systemic diseases that may correlate with periodontal health, such as diabetesrheumatic fever, liver or kidney disease, and neurological deficiencies
* Patients taking medication which may affect the periodontium (bisphosphonates, phenytoin, cyclosporin, nifidepine, chronic use of non-steroidal anti-inflammatory drugs)
* Patient who had taken systemic antibiotics up to 3 months prior to treatment or medical conditions requiring prophylactic antibiotic coverage
* Participation in any other clinical study
* Tobacco chewing or sniffing
18 Years
70 Years
ALL
Yes
Sponsors
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BioGaia AB
INDUSTRY
Sunstar
UNKNOWN
Cukurova University
OTHER
Responsible Party
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Mustafa Ozcan
Associate professor
Locations
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Cukurova university Faculty of Dentistry
Adana, , Turkey (Türkiye)
Countries
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Other Identifiers
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CukurovaU-PerII
Identifier Type: -
Identifier Source: org_study_id
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