Effect of Probiotics as Supplement to Non-surgical Periodontal Treatment
NCT ID: NCT05518747
Last Updated: 2022-11-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
NA
60 participants
INTERVENTIONAL
2022-09-01
2023-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Impact of Oral Probiotics on Oral Homeostasis
NCT04071210
Efficacy of Supplementation With Probiotics as Adjuvant to Mechanical Treatment in Chronic Periodontitis
NCT03554187
Effect of Probiotics on Oral Homeostasis During Oral Hygiene Discontinuation
NCT05268757
Effects of Prebiotic Oral Healthcare Products as an Adjunct to Non-surgical Periodontal Therapy
NCT02520375
Effects on Tablets Containing Probiotic Candidate Strains
NCT02633345
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
. 60 patients with periodontitis stage 2-3, grade B-C, generalized will be allocated in the test (probiotic) and the control (placebo) group at baseline.
The intervention is non-surgical periodontal treatment, which will be applied at baseline and followed for 12 weeks.
Clinical measurements and sampling will be performed at baseline, week 6 and week 12.
Primary endpoint: Changes in microbial composition.
Secondary endpoints: Changes in clinical and immunological parameters
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Probiotic
In this group participants will receive non-surgical periodontal treatment at baseline, which will for 12 weeks
Probiotic
In this group participants will receive probiotic supplements twice a day (morning and evening) for a period of 12 weeks.
Placebo
In this group participants will receive non-surgical periodontal treatment at baseline, which will for 12 weeks
Placebo
In this group participants will receive placebo twice a day (morning and evening) for at period of 12 weeks.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Probiotic
In this group participants will receive probiotic supplements twice a day (morning and evening) for a period of 12 weeks.
Placebo
In this group participants will receive placebo twice a day (morning and evening) for at period of 12 weeks.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
30 Years
70 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Copenhagen
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Daniel Belstrøm, DDS, PhD
Associate professor, dr. odont., PhD, DDS
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University of Copenhagen, Department of Odontology
Copenhagen, , Denmark
Countries
Review the countries where the study has at least one active or historical site.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
UCPH_01_007
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.