A Clinical Trial to Evaluate the Effectiveness of Lactobacillus Reuteri for Periodontitis in a Chinese Population
NCT ID: NCT04129684
Last Updated: 2020-05-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
880 participants
INTERVENTIONAL
2019-12-01
2021-11-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Test group
SRP+BioGaia Prodentis oil drops and lozenges
Probiotics
subgingival delivery and lozenges
Control group
SRP+subgingival delivery of placebo and placebo lozenges
Probiotics
subgingival delivery and lozenges
Interventions
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Probiotics
subgingival delivery and lozenges
Eligibility Criteria
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Inclusion Criteria
2. Patients diagnosed with periodontitis clinically evident according to International Classification of Periodontal Diseases (2017) with periodontal probing depth ≥4mm, attachment loss of the most severe site in the adjacent area ≥3mm, and imaging bone loss more than 1/3 of the root length
3. Natural teeth remaining in the mouth≥ 14
Exclusion Criteria
2. Patients with aggressive periodontitis.
3. Patients who received any periodontal treatment in the past 6 months
4. Pregnant or lactating women
5. Patients who smoke
6. Patients in the acute phase of an infectious disease
7. Patients taking bisphosphonate mediation
8. Patients who are on any probiotic, anticoagulants or antibiotic supplements for the past 3 months
9. Patients allergic to lactate products
10. Patients who are deemed uncooperative
18 Years
65 Years
ALL
No
Sponsors
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West China College of Stomatology
OTHER
Peking University Third Hospital
OTHER
Hospital of Stomatology, Jilin University
UNKNOWN
Second Affiliated Hospital, School of Medicine, Zhejiang University
OTHER
Responsible Party
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Locations
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Second Affiliated Hospital, School of Medicine
Hangzhou, Zhejiang University, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2019-1015
Identifier Type: -
Identifier Source: org_study_id
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