Protozoans in Biofilm From Patients With Periodontitis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

231 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-04-10

Study Completion Date

2022-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The buccal cavity is colonized by numerous microorganisms whose the number and composition could be modified with medical background (diseases and drugs) and the level of oral hygiene of the patients. Among all microorganisms identified in the periodontium, few of them are implicated in the etiopathogenesis of periodontal pathologies. To date, four major bacteria are identified for their ability to degrade periodontal tissues.

Although the periodontitis is established to be the consequence of bacterial virulence and immune dysfunction, these factors fail to explain the refractory periodontitis of some patients to etiologic treatment .

Others microorganisms such as protozoans could have an impact on this disease.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Clinical Study of the Presence of Trichomonas Tenax and Entamoeba Gingivalis in Patients With Periodontitis

NCT03178838

Periodontitis, Adult

COMPLETED

Implant Surface Decontamination in Peri-implantitis Treatment

NCT01521260

Peri-implantitis Periodontal Disease

COMPLETED NA

Microbial Associations in Periodontal Health and Disease

NCT00066001

Periodontitis Periodontal Diseases

COMPLETED PHASE2

Nalysis of the Periodontal Microbiota in Elderly Subjects With and Without Alzheimer's Disease: a Case Control Study

NCT05077618

Periodontitis Alzheimer Disease

RECRUITING

Efficacy of Supplementation With Probiotics as Adjuvant to Mechanical Treatment in Chronic Periodontitis

NCT03554187

Probiotics, Periodontitis

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Periodontitis, Adult

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

OTHER

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

non applicable

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Adults \> 18 years-old
* consulting in periodontal department of CHRU
* Patients with moderate to severe periodontitis
* At least 2 periodontal sites with PPD ≥ 5mm and one healthy site
* No scaling root planing in the last 6 months
* Patients insured under the Franch social security system

Exclusion Criteria

* Pregnants patients
* Patients with antibiotic therapy and/ or all medecines which could modify the buccal microbiota in the last 6 months
* Tooth with endodontics periapical lesion
* Patients having a scaling root planing in the last 6 months
* Patients with guardianship

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes