Garlic With Lime Juice and Chlorhexidine Mouthwash

NCT ID: NCT03105960

Last Updated: 2017-04-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-10

Study Completion Date

2017-06-01

Brief Summary

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the study about herbal mouthwash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and their effect on gingival bleeding and plaque and salivary bacteria.

Detailed Description

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the study about herbal mouth wash. it is clinical trial .the investigator will compare between chlorhexidine mouthwash and garlic with lime juice mouthwash.and show their effect on gingival bleeding and strepococcus bacteria present in saliva and plaque.

1. Preparation of garlic with lime juice will occur under aseptic condition.and give it to the first group.

provide chlorhexidine to the second group.
2. Collection of plaque and saliva samples will be obtained from children who fulfilled the inclusion criteria.
3. Asses gingival condition by asking patient.
4. Subjects will be instructed to rinse for 14 days, twice daily.
5. Morning after breakfast and night before going to bed.
6. With 10 ml (undiluted) of the assigned mouthwash for 30 s and then expectorate the rinse.
7. Again after 14 days, the saliva and plaque samples will be taken and inoculated on blood agar plates to determine the colony count and the gingival index by loe and illness will be assessed.

Conditions

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Gingival Bleeding

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

A Randomized Clinical Trial parallel
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators
This was a double-blind study as the investigator was unaware about the sampling of the groups and study subjects were unaware about the mouthwash they were using

Study Groups

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garlic with lime juice mouthwash

garlic with lime juice mouthwash is herbal antimicrobial .children were instructed to rinse for 14 days, twice daily, ,10 ml (undiluted) for 30 second and then expectorate .

To prepare garlic with lime mouth rinse, 100 g of fresh, washed garlic cloves was macerated in a sterile, ceramic mortar and water was added to obtain a homogenate which was then filtered off with a sterile muslin cloth. the final concentration of the solution was determined to be 1 g/100 ml. About 100 ml of lime juice was extracted from fresh lemons using a juice extractor and added to the garlic extract.

Group Type EXPERIMENTAL

garlic with lime mouth wash

Intervention Type DRUG

garlic with lime juice is herbal antimicrobial 10 ml (undiluted) for 30s and then expectorate for 14 days.o prepare garlic with lime mouth rinse, 100 g of fresh, washed garlic cloves was macerated in a sterile, ceramic mortar and water was added to obtain a homogenate which was then filtered off with a sterile muslin cloth. the final concentration of the solution was determined to be 1 g/100 ml. About 100 ml of lime juice was extracted from fresh lemons using a juice extractor and added to the garlic extract.

chlorhexidine mouthwash

chlorhexidine is antimicrobial, antiplaque mouthwash 10 ml (undiluted) for 30 second twice daily and then expectorate for 14 days. it is commercial mouthwash

.

Group Type ACTIVE_COMPARATOR

chlorhexidine

Intervention Type DRUG

hlorhexidine is antimicrobial, antiplaque mouthwash 10 ml (undiluted) for 30 second twice daily and then expectorate for 14 days.

Interventions

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garlic with lime mouth wash

garlic with lime juice is herbal antimicrobial 10 ml (undiluted) for 30s and then expectorate for 14 days.o prepare garlic with lime mouth rinse, 100 g of fresh, washed garlic cloves was macerated in a sterile, ceramic mortar and water was added to obtain a homogenate which was then filtered off with a sterile muslin cloth. the final concentration of the solution was determined to be 1 g/100 ml. About 100 ml of lime juice was extracted from fresh lemons using a juice extractor and added to the garlic extract.

Intervention Type DRUG

chlorhexidine

hlorhexidine is antimicrobial, antiplaque mouthwash 10 ml (undiluted) for 30 second twice daily and then expectorate for 14 days.

Intervention Type DRUG

Other Intervention Names

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herbal mouthwash antimicrobial mouthwash

Eligibility Criteria

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Inclusion Criteria

1. Children aged between 9 and 12 years.
2. Children are having normal occlusion (no crowding), non-compromised oral health (brushed their teeth once-daily) using toothbrush and non-fluoridated toothpaste. And practicing no other oral hygiene measures.
3. Medically free history.
4. Absence of orthodontic appliances.

Exclusion Criteria

1. History of current or recent (at least for the past 1 month) antibiotic usage or other medications.
2. Presence of Abscess, draining sinus, cellulitis, or other conditions requiring emergency dental treatment.
3. not willing to comply with the study.
Minimum Eligible Age

9 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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manal sayed abdel latief

oral and dental medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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sherif B eltweel, Ass.prof

Role: STUDY_DIRECTOR

Cairo univaesity

Locations

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Manal Sayed Abdel Latief

Helwan, Cairo Governorate, Egypt

Site Status

Countries

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Egypt

References

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Tulsani SG, Chikkanarasaiah N, Siddaiah SB, Krishnamurthy NH. The effect of Propolis and Xylitol chewing gums on salivary Streptococcus mutans count: a clinical trial. Indian J Dent Res. 2014 Nov-Dec;25(6):737-41. doi: 10.4103/0970-9290.152182.

Reference Type BACKGROUND
PMID: 25728105 (View on PubMed)

Related Links

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Other Identifiers

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151087

Identifier Type: REGISTRY

Identifier Source: secondary_id

151087

Identifier Type: -

Identifier Source: org_study_id

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