Clinical Evaluation and Assesment of Ginigivitis Patients Treated by Yarrow Natural Extract in Compare to a Contro Group

NCT ID: NCT06070571

Last Updated: 2023-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-05-20

Study Completion Date

2023-05-20

Brief Summary

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A double-blind, prospective, randomized, intra-individual comparative, single-center clinical study was conducted. Participants were placed in parallel groups, and the study was performed in the Department of Operative Dentistry and Periodontology, Dental School and Hospital, Minia university to compare the antibacterial activity of yarrow Moringa herbal combinations nanoparticles in compared to Chlorhexidine as a potential treatment for gingivitis.

Detailed Description

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Conditions

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Gingivitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Intervention group

Bucco-adhesive films with Yarrow and Moringa extract nanoparticles

Group Type EXPERIMENTAL

Yarrow and moringa mixture

Intervention Type DRUG

yarrow and moringa mixture nano particles loaded on buccal film

control group

Cholorohexiden oral gargles

Group Type ACTIVE_COMPARATOR

Yarrow and moringa mixture

Intervention Type DRUG

yarrow and moringa mixture nano particles loaded on buccal film

Interventions

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Yarrow and moringa mixture

yarrow and moringa mixture nano particles loaded on buccal film

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* a minimum of four natural uncrowned teeth in one quadrant present
* good general health
* can follow instructions

Exclusion Criteria

* were pregnant or breastfeeding
* evidence of antibiotic use during the 4 weeks prior to the study
* were allergic to personal care/consumer products or their ingredients
Minimum Eligible Age

25 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Deraya University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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soad ali, PhD

Role: STUDY_DIRECTOR

faculty of pharmacy, Deraya university

Locations

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Soad A. Mohamad

Minya, Minya Governorate, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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3/23

Identifier Type: -

Identifier Source: org_study_id

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