The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups

NCT ID: NCT06140394

Last Updated: 2024-06-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-29

Study Completion Date

2024-06-25

Brief Summary

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the summary is to evaluate The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients

Detailed Description

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2 ml of unstimulated saliva will be collected using spitting method, the collected samples will then be analyzed using Elisa technique for salivary Inducible nitrous oxide synthase levels.

Conditions

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Periodontal Inflammation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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old age group

old age group above 60 years old

Group Type ACTIVE_COMPARATOR

diode laser

Intervention Type OTHER

low level diode therapy

non surgical scaling

Intervention Type OTHER

non surgical scaling using ultrasonic

young aged group

young age group below 40 years old

Group Type PLACEBO_COMPARATOR

diode laser

Intervention Type OTHER

low level diode therapy

non surgical scaling

Intervention Type OTHER

non surgical scaling using ultrasonic

Interventions

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diode laser

low level diode therapy

Intervention Type OTHER

non surgical scaling

non surgical scaling using ultrasonic

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* males and females
* aged below 40 or above 60
* periodontitis stage 2
* no tooth loss due to periodontitis

Exclusion Criteria

* smoking habits
* history of antibiotics
* history of systemic diseases
Minimum Eligible Age

60 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Faculty of Dental Medicine for Girls

OTHER_GOV

Sponsor Role lead

Responsible Party

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Alaa Allah Hesham

Bachelor's Degree (research assistant)

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Alaa H hesham mosa, bachelor's

Role: STUDY_CHAIR

Faculty of Dental Medicine for Girls

hamdy H nassar

Role: PRINCIPAL_INVESTIGATOR

Faculty of Dental Medicine for Girls

amal AA ali

Role: STUDY_DIRECTOR

Faculty of Dental Medicine for Girls

Locations

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Al-Azhar University

Cairo, Nasrcity Nasr Street, Egypt

Site Status

Hamdy Nassar

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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P-ME-23-04

Identifier Type: -

Identifier Source: org_study_id

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