Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: a Relation to Periodontal Inflammaging

NCT ID: NCT06677736

Last Updated: 2024-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-12

Study Completion Date

2024-10-12

Brief Summary

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Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: A Relation to Periodontal Inflammaging

Detailed Description

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Effect of Low-Level Laser Therapy on Salivary Toll Like Receptor- 4 Concentration of Periodontitis Patients: A Relation to Periodontal Inflammaging

Conditions

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Periodontal Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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conventional scaling and debridement young age patient

conventional scaling and debridement young age patient

Group Type EXPERIMENTAL

conventional scaling and debridement

Intervention Type PROCEDURE

conventional scaling and debridement

conventional scaling and debridement old age patient

conventional scaling and debridement old age patient

Group Type EXPERIMENTAL

conventional scaling and debridement

Intervention Type PROCEDURE

conventional scaling and debridement

diode laser as adjunctive to scaling and debridement young age patient

diode laser as adjunctive to scaling and debridement young age patient

Group Type EXPERIMENTAL

Diode laser as adjunctive to conventional scaling and debridement

Intervention Type RADIATION

Diode laser as adjunctive to conventional scaling and debridement

diode laser as adjunctive to scaling and debridement old age patient

diode laser as adjunctive to scaling and debridement old age patient

Group Type EXPERIMENTAL

Diode laser as adjunctive to conventional scaling and debridement

Intervention Type RADIATION

Diode laser as adjunctive to conventional scaling and debridement

Interventions

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conventional scaling and debridement

conventional scaling and debridement

Intervention Type PROCEDURE

Diode laser as adjunctive to conventional scaling and debridement

Diode laser as adjunctive to conventional scaling and debridement

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

1. Male or Female
2. Aged below 40 or above 60.
3. Have at least 16 natural teeth excluding wisdom.
4. Provide informed consent and willingness to cooperate with study protocol.
5. Periodontitis stage II patients (23):

* CAL from 3-4 mm.
* Radiographic bone loss (15% to 33%).
* No tooth loss due to periodontitis.
* Maximum probing depth ≤ 5 mm, mostly horizontal bone loss

Exclusion Criteria

* 1- Patients with any smoking habits 2- History of antibiotics in the previous three months. 3- Pregnant or lactating female. 4- Treatment with any systemic drug. 5- History of systemic disease. 6- Patients who received periodontal treatment in the last 6 months
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rawda Saleh Saad Alashmawy

OTHER

Sponsor Role lead

Responsible Party

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Rawda Saleh Saad Alashmawy

dentist

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Misr university for science and technology

Giza, Giza Governorate, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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2022\0083

Identifier Type: -

Identifier Source: org_study_id

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