Comparing Photodisinfection of Chitosan NP Enriched ICG Over ICG as Adjunct to OFD: RCT
NCT ID: NCT06523244
Last Updated: 2024-07-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
24 participants
INTERVENTIONAL
2024-07-31
2025-08-31
Brief Summary
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Detailed Description
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Test group (n=12) - PDT with Chitosan nanoparticles enriched ICG Control group(n=12) - PDT with ICG Microbial levels of P.gingivalis is analysed with PCR analysis on baseline and 3 months after intervention.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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test group
PDT with chitosan nanoparticles enriched ICG
PHOTODYNAMIC THERAPY
Respective photosensitive dye solution is applied on to the surgical site, including all the root surfaces. Vacuum suction is used to remove the excess dye from the site and to prevent ingestion of the dye solution The dye is activated with 810nm diode laser with continuous wave frequency and power of 0.3 W with 400 µm fiber tip for 20 seconds/spot. After this, the area is irrigated with saline.
Control group
PDT with ICG
PHOTODYNAMIC THERAPY
Respective photosensitive dye solution is applied on to the surgical site, including all the root surfaces. Vacuum suction is used to remove the excess dye from the site and to prevent ingestion of the dye solution The dye is activated with 810nm diode laser with continuous wave frequency and power of 0.3 W with 400 µm fiber tip for 20 seconds/spot. After this, the area is irrigated with saline.
Interventions
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PHOTODYNAMIC THERAPY
Respective photosensitive dye solution is applied on to the surgical site, including all the root surfaces. Vacuum suction is used to remove the excess dye from the site and to prevent ingestion of the dye solution The dye is activated with 810nm diode laser with continuous wave frequency and power of 0.3 W with 400 µm fiber tip for 20 seconds/spot. After this, the area is irrigated with saline.
Eligibility Criteria
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Inclusion Criteria
* Age group 30-55yrs.
* Diagnosed with Stages II/III grade B/C periodontitis.
* Presenting with persistent pocket depth ≥5mm after initial non-surgical therapy.
* Optimal plaque control
* Good compliance
Exclusion Criteria
* Previous history of periodontal surgery
* Allergy to drugs and materials used in this study
* Pregnant woman
* Subjects with deleterious habits like smoking, tobacco chewing.
30 Years
55 Years
ALL
Yes
Sponsors
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Krishnadevaraya College of Dental Sciences & Hospital
OTHER
Responsible Party
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Central Contacts
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Other Identifiers
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02_D012_00046
Identifier Type: -
Identifier Source: org_study_id
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