Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE1
124 participants
INTERVENTIONAL
2024-03-24
2024-06-25
Brief Summary
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Detailed Description
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In this study, 124 standardized size-80 gutta-percha (GP) cones (Dentsply, Germany) were used to assess the efficacy of chemical disinfectants.
The cones were first sterilized using ethylene oxide to ensure baseline sterility. Following sterilization, 124 cones were allocated into two experimental groups (n = 62 each) for contamination.
group A . gp were immersed in 20ml of Enterococcus faecalis solution group B . gp were immersed in 20 ml of human saliva in patients undergoing root canal therapy
samples were incubated at 37°C for 72 hours to ensure uniform and thorough contamination
after incubation period cones were dried and divide into subgroups based on disinfectant agent applied .
The cones were immersed in disinfectant agent for 1 min and 10 min . Cones were dried again and immersed in brain heard infusion broth samples were again incubated at 37°C for 72 hours The presence of bacterial growth was determined by assessing turbidity in the broth, indicating viable microorganisms.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
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Naocl group
In this group, the Gp cones would be submerged in 5% naocl solution for 5 minutes and then tested for biofilm removal and eradication of inoculated microorganisms.
Sodium Hypochlorite
Sodium hypochlorite used in 5% concentration for disinfection
chlorhexidine group
In this group, the Gp cones would be submerged in 0.2% chlorhexidine solution for 5 minutes and then tested for biofilm removal and eradication of inoculated microorganisms.
Chlorhexidine
Chlorhexidine 0.2% concentration for disinfection
Interventions
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Sodium Hypochlorite
Sodium hypochlorite used in 5% concentration for disinfection
Chlorhexidine
Chlorhexidine 0.2% concentration for disinfection
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
20 Years
40 Years
ALL
Yes
Sponsors
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Armed Forces Institute of Dentistry, Pakistan
OTHER
Responsible Party
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Hira Amjad
Dr. Hafiza Hira Amjad
Principal Investigators
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Hafiza Hira Amjad, BDS
Role: PRINCIPAL_INVESTIGATOR
Armed Forces Institute of Dentistry
Locations
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Armed Forces Institute of Dentistry
Rawalpindi, Punjab Province, Pakistan
Countries
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Other Identifiers
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Disinfection
Identifier Type: -
Identifier Source: org_study_id
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