Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions
NCT ID: NCT06933290
Last Updated: 2025-04-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
13 participants
INTERVENTIONAL
2025-03-24
2025-06-29
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
SINGLE
Study Groups
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Flavored carbonated drink 1
Flavored carbonated beverage with nutritive sweeteners
Beverage
15 milliliter aliquot interspersed with tastants with a 3 minute break between tastants
Flavored carbonated drink 2
Flavored carbonated beverage with non-nutritive sweeteners
Beverage
15 milliliter aliquot interspersed with tastants with a 3 minute break between tastants
Flavored drink
Flavored non-carbonated beverage with nutritive sweeteners
Beverage
15 milliliter aliquot interspersed with tastants with a 3 minute break between tastants
Flavored non-carbonated drink
Flavored non-carbonated beverage with non-nutritive sweeteners
Beverage
15 milliliter aliquot interspersed with tastants with a 3 minute break between tastants
Carbonated Water
Unflavored carbonated water
Beverage
15 milliliter aliquot interspersed with tastants with a 3 minute break between tastants
Water
Plain, unflavored, non-carbonated water
Beverage
15 milliliter aliquot interspersed with tastants with a 3 minute break between tastants
Interventions
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Beverage
15 milliliter aliquot interspersed with tastants with a 3 minute break between tastants
Eligibility Criteria
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Inclusion Criteria
* If female, subject is not pregnant or nursing (based on self-report)
* Subject is 18-45 years of age, inclusive
* Subject is a regular consumer of carbonated drinks (questionnaire)
* Subject is willing to avoid alcohol consumption 24 hours prior to visits
* Subject is willing to fast (no food or gum) for 2 hours prior to study sessions
* Able to speak, write, and read English
* Provision of written consent to participate
Exclusion Criteria
* Subject currently has or recently had an illness (cold, flu, COVID) within the past month
* Subject has a condition affecting the oral cavity such as Xerostomia (dry mouth), Sores/lesions, Untreated dental caries, Major dental implants/appliances (including dentures)
* Subject has a reduced sense of taste (dysgeusia) or smell (parosmia)
* Subject has a health condition that would interfere with the study as indicated on the general health questionnaire (GHQ) (including cardiovascular, renal, or metabolic diseases)
* Subject has participated in a clinical trial within the past 30 days
* Subject has participated in any PepsiCo trial within past 6 months
* Subject has a condition or is taking medication that the investigator believes would interfere with his/her ability to provide informed consent, comply with the study protocol, which might confound the interpretation of the study results, or put the person at undue risk
* Subject is employed by, or has a parent, guardian, or other immediate family member employed by a company that manufactures any products that compete with any PepsiCo product. If subject is unsure if a company would be considered a competitor to PepsiCo, they will be asked to please let the study investigator know the name of the other company and the nature of their relationship to that company before they sign the informed consent.
18 Years
45 Years
ALL
Yes
Sponsors
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PepsiCo Global R&D
INDUSTRY
Responsible Party
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Principal Investigators
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Lindsay Baker, PhD
Role: PRINCIPAL_INVESTIGATOR
PepsiCo, Inc. Sports Science
Locations
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Gatorade Sports Science Institute
Valhalla, New York, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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PEP-2423
Identifier Type: -
Identifier Source: org_study_id
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