Efficacy of Licorice on Reducing Salivary Streptococcus Mutans Versus Chlorohexidine in Caries Risk Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-01

Study Completion Date

2019-10-01

Brief Summary

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To compare the effect of a natural herbal licorice containing preventive measure alternative to chlorohexidine preventive measure to decrease the effect of streptococcus mutans.

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Detailed Description

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A total number of fifty-two patients will be enrolled in the study. They will be divided into two groups: study group and control group. Study group will be subjected to licorice mouthwash and the control will be subjected to chlorohexidine mouth wash. Salivary bacterial count will be evaluated for both groups.

Conditions

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Caries, Dental

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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licorice extract mouthwash

administration of a mouthwash containing licorice as a preventive measure to high caries risk patients (faculty of pharmacy, cairo university)

Group Type EXPERIMENTAL

licorice extract mouthwash

Intervention Type OTHER

mouth rinse that contains a natural herbal licorice root extract used as a preventive measure that reduce caries index.

chlorohexidine mouthwash

administration of chlorohexidine 0.2% in 1:1 diluation mouthwash that is broad spectrum antimicrobial activity to high caries risk patients

Group Type PLACEBO_COMPARATOR

chlorohexidine mouthwash

Intervention Type OTHER

mouth wash that contains chlorohexidine as an active component

Interventions

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licorice extract mouthwash

mouth rinse that contains a natural herbal licorice root extract used as a preventive measure that reduce caries index.

Intervention Type OTHER

chlorohexidine mouthwash

mouth wash that contains chlorohexidine as an active component

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* over 18 years old
* co-operative patients
* not allergic to licorice
* not allergic to chlorohexidine

Exclusion Criteria

* pregnancy
* allergic patients to licorice
* allergic patients to chlorohexidine
* lack of compliance
* evidence of parafunctional habits
* patients with periodontal disease
* xerostomia
* participants that receive any microbial agent two weeks prior to the study

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes