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Salivary Flow Rate and Oral Function

NCT ID: NCT01020084

Last Updated: 2009-11-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-08-31

Study Completion Date

2007-11-30

Brief Summary

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The purpose of this study was to investigate if salivary flow rate is important to maintain adequate oral functions.

Detailed Description

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Hyposalivation may damage oral functions. Therefore, the aim of this study was to evaluate whether patients under hyposalivation present damaged mastication and speech. Forty subjects composed 2 groups: Control (C) and hyposalivation (H). Masticatory performance (MP) was carried out using artificial material and a 10-sieve method. Mandibular movements during speech were obtained using a 3D jaw-tracking device. Neither mastication nor speech have been impaired by low salivary flow rate.

Conditions

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Food Comminution Jaw Movements

Keywords

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Saliva Mastication Communication

Study Design

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Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Control

Subjects with normal salivary flow rate

No interventions assigned to this group

Hyposalivation

Subjects presenting low salivary flow rate as a side effect of systemic isotretinoin therapy.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Fully dentate
* Good general and oral health

Exclusion Criteria

* Signs or symptoms of temporomandibular disorders
* Parafunctions
* Malocclusion
* History of communication deficits or prior speech-language treatment
Minimum Eligible Age

16 Years

Maximum Eligible Age

27 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

Sponsor Role collaborator

University of Campinas, Brazil

OTHER

Sponsor Role lead

Responsible Party

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Piracicaba Dental School, State University of Campinas

Principal Investigators

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Renata CM Rodrigues Garcia, PhD

Role: STUDY_CHAIR

Piracicaba Dental School

Alrair A Del Bel Cury, PhD

Role: STUDY_DIRECTOR

Piracicaba Dental School

Simone G Farias Gomes, MS

Role: PRINCIPAL_INVESTIGATOR

Piracicaba Dental School

Locations

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Piracicaba Dental School

Piracicaba, São Paulo, Brazil

Site Status

Countries

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Brazil

References

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Saliva: its role in health and disease. Working Group 10 of the Commission on Oral Health, Research and Epidemiology (CORE). Int Dent J. 1992 Aug;42(4 Suppl 2):287-304. No abstract available.

Reference Type BACKGROUND
PMID: 1399047 (View on PubMed)

Bianchini EM, de Andrade CR. A model of mandibular movements during speech: normative pilot study for the Brazilian Portuguese language. Cranio. 2006 Jul;24(3):197-206. doi: 10.1179/crn.2006.032.

Reference Type BACKGROUND
PMID: 16933461 (View on PubMed)

Liedberg B, Owall B. Masticatory ability in experimentally induced xerostomia. Dysphagia. 1991;6(4):211-3. doi: 10.1007/BF02493529.

Reference Type RESULT
PMID: 1778098 (View on PubMed)

Ishijima T, Koshino H, Hirai T, Takasaki H. The relationship between salivary secretion rate and masticatory efficiency. J Oral Rehabil. 2004 Jan;31(1):3-6. doi: 10.1111/j.1365-2842.2004.01033.x.

Reference Type RESULT
PMID: 15125589 (View on PubMed)

Other Identifiers

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monegfg09

Identifier Type: -

Identifier Source: org_study_id