Efficacy of Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-12

Study Completion Date

2025-06-11

Brief Summary

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This study aims to compare efficacy of sedation between Dexmedetomidine-Propofol and Ketamine-Propofol combinations in the upper or lower gastrointestinal system endoscopy. We compare between 2 combinations as regard hemodynamic stability, post operative side effects as occurrence of delirium, nausea, vomiting, headache, hallucination or agitation.

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Detailed Description

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Conditions

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Propofol

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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Dexmedetomidine-Propofol for sedation during gastrointestinal endoscopy

efficacy of sedation with Dexmedetomidine-Propofol combination in the upper or lower gastrointestinal system endoscopy.

Group Type ACTIVE_COMPARATOR

Dexmedetomidine-Propofol

Intervention Type DRUG

efficacy of sedation with Dexmedetomidine-Propofol combination in the upper or lower gastrointestinal system endoscopy.

Ketamine-Propofol for sedation during gastrointestinal endoscopy

efficacy of sedation with Ketamine-Propofol combination in the upper or lower gastrointestinal system endoscopy.

Group Type ACTIVE_COMPARATOR

Ketamine-Propofol

Intervention Type DRUG

efficacy of sedation with Ketamine-Propofol combination in the upper or lower gastrointestinal system endoscopy.

Interventions

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Dexmedetomidine-Propofol

efficacy of sedation with Dexmedetomidine-Propofol combination in the upper or lower gastrointestinal system endoscopy.

Intervention Type DRUG

Ketamine-Propofol

efficacy of sedation with Ketamine-Propofol combination in the upper or lower gastrointestinal system endoscopy.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* American Society of Anesthesiologists physical status I to II.
* Age between 18 and 60 years.
* Both sexes.

Exclusion Criteria

* Having severe heart, lung, liver disease, kidney failure, or bleeding disorder.
* Patients having fever, hypothermia or infection, electrolyte disorders, such as hypokalemia and hypocalcaemia, acid-base disorder, allergy to drugs to be used.

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No