Application of CIELab Spectrophotometry to Analyze Gingival Color: a New Perspective for Evaluating the Effectiveness of Periodontal Basic Treatment
NCT ID: NCT06698718
Last Updated: 2024-11-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
30 participants
INTERVENTIONAL
2024-10-18
2025-03-01
Brief Summary
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Method: This study aims to include 30 periodontitis patients who visited the Periodontology Department of the Second Affiliated Hospital of Zhejiang University School of Medicine from October 2024 to November 2024. The study adopted a self controlled before and after design. All subjects received periodontal basic treatment. Record the age, gender, ethnicity, skin color, and gingival biotype of the subjects. Before treatment, 6 weeks after treatment, and 12 weeks after treatment, check and record the blood routine, high-sensitivity C-reactive protein (Hs CRP), and interleukin-6 (IL-6) of all subjects. Use a moisture absorbing paper tip to collect the gingival crevicular fluid of the subjects, and further detect the levels of interleukin-17 (IL-17) and tumor necrosis factor alpha (TNF - α) in the gingival crevicular fluid samples, and record the periodontal table. Check and record the CIE indicators L \*, a \*, b \*, probing depth (PD), gingival bleeding index (SBI), and clinical attachment loss (CAL) in the keratinized gingival area of all subjects before and after treatment at 2, 6, and 12 weeks. Analyze and compare the changes in each group's data before and after treatment.
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Treatment group
Periodontal basic treatment
Accept periodontal basic treatment
Interventions
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Periodontal basic treatment
Accept periodontal basic treatment
Eligibility Criteria
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Inclusion Criteria
2. I haven't received any periodontal basic treatment, including scaling, scraping, flap surgery, etc., for the past six months
3. The anterior teeth area has not undergone periodontal surgery or coronal restoration within six months
4. The patient has clear thinking, unobstructed communication, and high compliance
Exclusion Criteria
2. Blood pressure\>180/110 mmHG
3. Pregnant women, women in pregnancy or lactation
4. Those who are currently taking anticoagulant drugs, calcium channel blockers, immunosuppressants, angiotensin and other medications, receiving bisphosphonates treatment, or have a history of antibacterial treatment within 3 months
5. Uncontrolled and stable patients with systemic diseases, such as progressive liver diseases, infectious diseases, renal failure, rheumatoid diseases, blood system diseases, osteoporosis, AIDS, mental diseases and diabetes, etc
6. Patients with malignant tumors or undergoing radiotherapy, chemotherapy, and targeted drug therapy
7. Patients with pacemakers who cannot undergo ultrasound therapy
8. Smoking or quitting smoking for less than 5 years
9. Individuals with abnormalities such as pigment deposition and keratinized beads in the front teeth and gums
18 Years
65 Years
ALL
No
Sponsors
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Second Affiliated Hospital, School of Medicine, Zhejiang University
OTHER
Responsible Party
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Locations
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2 nd Affiliated Hospital, School of Medicine, Zhejiang University, China
Hangzhou, Zhejiang, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2023-0935
Identifier Type: -
Identifier Source: org_study_id
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