Study on the Relationship Between Periodontitis and Renal Disease

NCT ID: NCT02417363

Last Updated: 2015-04-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-10-31

Study Completion Date

2016-10-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Analysis of inflammatory markers in periodontitis and patients with early and middle stage renal disease.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

A total of 200 population is recruited, individuals are divided into four groups according to a periodontal examination and a general physical examination: healthy individuals ,periodontitis, renal disease patients with healthy periodontium, and renal disease patients wth peridontitis. Fasting blood samples and gingival crevicular fluid are collected from all individuals, and inflammatory markers are analysed for the four groups.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Periodontitis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CROSSOVER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group A

the control group,healthy individuals

No interventions assigned to this group

Group B

patients with 1-4 stage K/DOQI (Kidney Disease Outcome Quality Initiative) chronic kidney disease, but healthy periodontium

No interventions assigned to this group

Group C

patients with periodontitis, but healthy renal conditions

No interventions assigned to this group

Group D

patients with 1-4 stage K/DOQI (Kidney Disease Outcome Quality Initiative) chronic kidney disease and periodontitis

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* all participants were in general good health(except renal disease) and non-smoking

Exclusion Criteria

* less than 20 teeth in the dentin
* hypertension
* the presence of systemic disease (e.g., diabetes mellitus ,coronary heart disease, liver, or lung disease)
* a history or the symptom of any other acute or chronic infections
* systemic antibiotic treatment within previous 4 weeks
* periodontal treatment within1 month
Minimum Eligible Age

25 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Na Zhou

The stomatological hospital affiliated to medical college, Zhejiang University

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Hui Chen

Role: STUDY_DIRECTOR

Affiliated Hospital of Stomatology, School of Medicine, Zhejiang University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Affiliated Hospital of Stomatology, School of Medicine, Zhejiang University

Hangzhou, Zhejiang, China

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

China

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Na Zhou

Role: CONTACT

86-571-87217437

Yan Tu

Role: CONTACT

86-571-87217437

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Na Zhou

Role: primary

86-571-87217437

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

ZJUSH2015-1

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Periodontitis and Inflammation
NCT04831060 RECRUITING
Outcomes of Periodontal Regenerative Treatment
NCT04971174 ENROLLING_BY_INVITATION