Effect of Low-Level Laser on Crevicular Interleukin-1β Concentration in Patients With Periodontal Disease: A Relation to Periodontal Inflammaging

NCT ID: NCT06677385

Last Updated: 2025-02-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-12

Study Completion Date

2024-10-12

Brief Summary

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This study is done to compare between young age and old age patients with periodontitis (inflammaging) and the effect of diode laser as adjunctive to scaling and debridement

Detailed Description

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Conditions

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Periodontal Diseases Old Age

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Conventional scaling and debridement in young aged patients

scaling and debridement

Group Type EXPERIMENTAL

conventional scaling and debridement

Intervention Type PROCEDURE

conventional scaling and debridement

Conventional scaling and debridement of old aged patients

Group Type EXPERIMENTAL

conventional scaling and debridement

Intervention Type PROCEDURE

conventional scaling and debridement

diode laser as adjunctive to conventional scaling and debridement for old age patients

Group Type EXPERIMENTAL

diode laser as adjunctive to conventional scaling and debridement

Intervention Type RADIATION

diode laser as adjunctive to conventional scaling and debridement for old age patients

diode laser as adjunctive to conventional scaling and debridement for young age patients

Group Type EXPERIMENTAL

diode laser as adjunctive to conventional scaling and debridement

Intervention Type RADIATION

diode laser as adjunctive to conventional scaling and debridement for old age patients

Interventions

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diode laser as adjunctive to conventional scaling and debridement

diode laser as adjunctive to conventional scaling and debridement for old age patients

Intervention Type RADIATION

conventional scaling and debridement

conventional scaling and debridement

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Male or Female
2. Aged below 40 or above 60.
3. Provide informed consent and willingness to cooperate with study protocol.
4. Periodontitis stage II patients:

* CAL from 3-4 mm.
* Radiographic bone loss (15% to 33%).
* No tooth loss due to periodontitis.
* Maximum probing depth ≤ 5 mm, mostly horizontal bone loss

Exclusion Criteria

1. Patients with heavy smoking habits
2. History of antibiotics in the previous three months.
3. Pregnant or lactating female.
4. Treatment with any systemic drug.
5. History of systemic disease.
6. Patients who received periodontal treatment in the last 6 months
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Misr University for Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Asmaa EssamEldin Ahmed

Teaching assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Misr University foe Science and Technology

Giza, Giza Governorate, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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2022/0082

Identifier Type: -

Identifier Source: org_study_id

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