Periodontal Treatment With Diode Laser in the Patients With Diabetes Melitus

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-09-20

Study Completion Date

2014-12-23

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study aimed to investigate the effects of diode laser (DL) in addition to non-surgical periodontal treatment on periodontal parameters, systemic inflammatory response, and serum hemoglobin A1c (HbA1c) level in patients with uncontrolled type 2 diabetes mellitus (T2DM) and chronic periodontitis.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Effect of Non-surgical Periodontal Treatment on HbA1c in Type 2 Diabetic Patients

NCT02652026

Chronic Periodontitis Type 2 Diabetes Mellitus

COMPLETED NA

Diode Laser Application With Non-Surgical Periodontal Treatment

NCT04908098

Periodontitis

UNKNOWN NA

Diode Laser-Assisted Periodontal Therapy Enhances Clinical Outcomes for Deep Periodontal Pockets in Smokers

NCT07213752

Periodontitis Periodontitis Stage III Periodontal Disease +3 more

COMPLETED NA

Low-level Laser Therapy in the Treatment of Chronic Periodontitis in Type 2 Diabetics

NCT02817152

Chronic Periodontitis Diabetes Mellitus

COMPLETED NA

Laser Biostimulation in Periodontal Treatment

NCT04253613

Periodontal Inflammation Periodontal Diseases

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This study was designed as a randomized, controlled, full-mouth, 6-month clinical trial. 37 patients (20 women and 17 men) with uncontrolled T2DM and chronic periodontitis who were selected from among those admitting to Dentistry Faculty of Inonu University and Turgut Ozal Medical Center completed this study. The patients were divided into two groups. The individuals in the control group underwent placebo laser treatment in addition to scaling and root planing (SRP). The individuals in the study group underwent DL (1 W power) in addition to SRP. Clinical index measurements were performed before treatment (T0), 3 months after treatment (T1), and 6 months after treatment (T2). Plaque index (PI), gingival index (GI), bleeding on probing (BOP), clinical attachment level (CAL), and probing depth (PD) were measured to determine periodontal status. HbA1c and C-reactive protein (CRP) levels were also analyzed using blood samples.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Diabetes Mellitus Periodontal Disease

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This study was designed as a randomized, controlled.

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

The results of the study were evaluated in a blinded manner

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Study group

SRP plus diode laser (810 nm wavelength, 1 W power)

Group Type EXPERIMENTAL

Laser group

Intervention Type DEVICE

Laser application in addition to SRP

Control group

SRP plus placebo

Group Type ACTIVE_COMPARATOR

Control group

Intervention Type DEVICE

Placebo laser application in addition to SRP

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Laser group

Laser application in addition to SRP

Intervention Type DEVICE

Control group

Placebo laser application in addition to SRP

Intervention Type DEVICE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Gigaa Laser

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Having a diagnosis of type-2 DM according to the ADA criteria for at least two years before the study, HbA1c⩾7%,28
* Having no change in antidiabetic drugs in the last 3 months,
* Having no major diabetes complications (because chronic complications of diabetes complicate metabolic control),
* Presence of generalized CP,29
* Presence of an area with a pocket depth of 4-7 mm in at least four teeth in the upper jaw,
* Presence of at least 20 teeth in the mouth,
* Having no any systemic illness except for DM,
* Having no smoke,
* Receiving no periodontal treatment in the last 12 months,
* Receiving no antibiotics or anti-inflammatory drugs for a long period in the last 6 months,
* Not being pregnant or not to breastfeed,
* Having no third molars.