Impact of Minimally Invasive Non-surgical Periodontal Treatment on Infrabony Defects

NCT ID: NCT06992219

Last Updated: 2025-05-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-10-01

Study Completion Date

2024-11-30

Brief Summary

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Fifty-two periodontitis patients (26 per group) were randomly assigned to the test (Minimally invasive non-surgical therapy - MINST) or the control group (Quadrantwise Subgingival Instrumentation - Q-SI) NPT protocols.

Detailed Description

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Clinical periodontal parameters, the number of pocket sites, x-ray of the infrabony defects characteristics and a composite outcome measure (COM) on the combined assessment of intrabony defect were recorded at baseline, and -3, 6- and at 12-months after treatment

Conditions

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Periodontal Intrabony Defect

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Non-surgical periodontal treatment Subgingival biofilm ultrasonic debridement with MINST or Q-SI for infrabony defects
Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors
Sealed envelopes

Study Groups

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MINST non surgical periodontal treatment

MINST non surgical periodontal treatment Periodontitis patients treated by means of MINST for infrabony defects. Patients were treated with non-surgical MINST periodontal treatment in a single session.

Group Type EXPERIMENTAL

Non surgical periodontal treatment evaluated through probing pocket depth reduction

Intervention Type OTHER

Patients were treated with Minimally invasive non surgical treatment (MINST) or quadrant-subgingival instrumentation (Q-SI). The efficacy of treatment in both groups was evaluated through Probin Pocket Depth reduction in millimetres measurement before and after treatment.

Q-SI non surgical periodontal treatment

Periodontitis patients treated by means of Q-SI. Patients were treated with non-surgical quadrantwise periodontal treatment in 4 sessions, 1 session per week.

Group Type ACTIVE_COMPARATOR

Non surgical periodontal treatment evaluated through probing pocket depth reduction

Intervention Type OTHER

Patients were treated with Minimally invasive non surgical treatment (MINST) or quadrant-subgingival instrumentation (Q-SI). The efficacy of treatment in both groups was evaluated through Probin Pocket Depth reduction in millimetres measurement before and after treatment.

Interventions

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Non surgical periodontal treatment evaluated through probing pocket depth reduction

Patients were treated with Minimally invasive non surgical treatment (MINST) or quadrant-subgingival instrumentation (Q-SI). The efficacy of treatment in both groups was evaluated through Probin Pocket Depth reduction in millimetres measurement before and after treatment.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of Periodontitis

Exclusion Criteria

* Periodontal treatment
* Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months
* Pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Catania

OTHER

Sponsor Role lead

Responsible Party

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Gaetano Isola

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gaetano Isola, DDS

Role: PRINCIPAL_INVESTIGATOR

Università degli Studi di Catania

Locations

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AOU Policlinico G. Rodolico

Catania, , Italy

Site Status

Countries

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Italy

Other Identifiers

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2024-3308

Identifier Type: -

Identifier Source: org_study_id

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