Grafting of the Peri-implant Bony Defects Around Immediate Implants Using Xenogenic Versus Alloplastic Sticky Grafts: Randomized Controlled Clinical Trial

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-20

Study Completion Date

2026-03-20

Brief Summary

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In patients with a single non restorable tooth, does filling the peri-implant buccal gap with alloplastic sticky grafts result comparable results compared to xenogenic sticky grafts?

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Detailed Description

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The buccal aspect of the dental implant has great importance, especially in the aesthetic zone, because the buccal bone is very thin especially in the anterior maxilla and its resorption can result in recession of the soft tissue. A gap occurs in immediately placed implant due to discrepancy between the dimensions of the extraction socket and the implant. Augmentation of the buccal gap decreases the amount of buccal bone resorption and soft tissue recession . Filling the peri-implant defects has been widely discussed to prevent further bone loss. The use of biologic materials such as platelet rich fibrin can enhance the quality of alloplastic bone grafts to give comparable effect when compared to xenogenic grafts.

Conditions

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Bone Loss, Alveolar

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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immediate implant placement surgery with filling the gap distance with alloplastic sticky graft

immediate implant placement surgery with filling the gap distance with injectable platelet rich fibrin combined with alloplast.

Group Type EXPERIMENTAL

dental implant with bone augmentation

Intervention Type PROCEDURE

gap distance augmentation with bone graft

immediate implant placement surgery with filling the gap distance with xenogenic sticky bone

immediate implant placement surgery with filling the gap distance with injectable platelet rich fibrin combined with xenograft.

Group Type EXPERIMENTAL

dental implant with bone augmentation

Intervention Type PROCEDURE

gap distance augmentation with bone graft

Interventions

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dental implant with bone augmentation

gap distance augmentation with bone graft

Intervention Type PROCEDURE

Other Intervention Names

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gap distance augmentation

Eligibility Criteria

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Inclusion Criteria

1. Patients with healthy systemic condition (Mazzotti et al., 2023).
2. Age from 20-50 years old
3. Patients must be free of any systemic disease which could influence the surgical procedure.
4. Tooth involved in the esthetic zone.
5. Sufficient hard and soft tissue volume in vertical and buccolingual direction
6. Natural teeth adjacent to the involved tooth will be required to be free from infection.
7. Controlled oral hygiene.
8. Indication for tooth extraction included (Degidi et al., 2012);

* Endodontic failures
* Untreatable caries
* Non- restorable teeth
* Vertical root fracture
* Remaining roots

Exclusion Criteria

\- 1.Pregnant females 2.Smokers (Khuller, 2009) 3.Unmotivated and uncooperative patients with poor oral hygiene 4.Patients with habits that may compromise the longevity and affect the result of the study as alcoholism or parafunctional habits.

5.Presence of acute dento-alveolar infection.

Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes