Autogenous Tooth Bone Graft Versus Allogeneic Bone Graft Around Dental Implant in Aesthetic Zone
NCT ID: NCT06773104
Last Updated: 2025-12-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
24 participants
INTERVENTIONAL
2024-03-25
2025-06-16
Brief Summary
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• Allogeneic bone graft group (control group): 12 patients will have immediate implant placement with allogeneic bone graft (demineralized freeze dried bone allograft - cortico cancellous).
Detailed Description
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• Allogeneic bone graft group (control group): 12 patients will have immediate implant placement with allogeneic bone graft (demineralized freeze dried bone allograft - cortico cancellous).
preparation of autogenous tooth bone graft Any restorations, caries, cementum, periodontal ligament and pulp tissue will be removed .The tooth will be grinded using dental bone mill and bone crusher Tooth particles will be sieved to particles size 300 to 1200 microns. The sorted particles will be immersed in 70 % ethanol and 5% Peracetic acid\* in a sterile container for 10 minutes to remove any soft tissue remnants, bacteria and smear layer (defatting and sterilization).
Tooth particles will be demineralized using 2% HNO3for 20 minutes to expose the dentine organic matrix.
The bacteria-free particulate dentin will be washed with phosphate buffered saline‡ twice for 5 minutes to restore the PH balance to 7.4. In the same setting, surgical procedure after atraumatic extraction immediate implant willbe inserted according to dimensions taken from CBCT and jumbing gap will be filled with bone graft according to randomization
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Autogenous tooth bone graft group
Twelve patients receiving immediate implant placement with autogenous fresh partially demineralized dentin graft.
Allogeneic bone graft with immediate implant placement
Immediate dental implant placement with grafting of the jumping gap using allogeneic bone graft (DFDBA).
Allogeneic bone graft group (control group)
Patients receiving immediate dental implant placement with allogeneic bone graft (DFDBA) for grafting of the jumping gap.
immediate implant with allogenic bone graft
after atraumatic extraction immediate implant will be inserted with allogenic bone graft
Interventions
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immediate implant with allogenic bone graft
after atraumatic extraction immediate implant will be inserted with allogenic bone graft
Allogeneic bone graft with immediate implant placement
Immediate dental implant placement with grafting of the jumping gap using allogeneic bone graft (DFDBA).
Eligibility Criteria
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Inclusion Criteria
* Thin labial plate of bone of the tooth to be extracted.
* Patients age above 20years old.
* Good oral hygiene.
* No signs of acute infection or inflammation
Exclusion Criteria
* Soft and hard tissue pathology at the operation site.
* Any relevant systemic disease or medication that might compromise bone healing.
18 Years
55 Years
ALL
Yes
Sponsors
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Tanta University
OTHER
Responsible Party
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Diab Abdel Gaied Diab Ghanem Mohammed
principal investigator
Principal Investigators
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diab abdelgaied diab, master
Role: PRINCIPAL_INVESTIGATOR
faculty of dentistry tanta university
Rafic ramadan bedir, professor
Role: PRINCIPAL_INVESTIGATOR
faculty of dentistry tanta university
Ibrahim mohammed nowair, professor
Role: PRINCIPAL_INVESTIGATOR
faculty of dentistry tanta university
Mona samy sheta, lecturer
Role: PRINCIPAL_INVESTIGATOR
faculty of dentistry tanta university
Locations
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Faculty of Dentistry
Tanta, , Egypt
Countries
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Other Identifiers
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diab123
Identifier Type: -
Identifier Source: org_study_id