Using the Roots of a Non Restorable Wisdom Tooth as a Block for Augmentation of Localized Defects

NCT ID: NCT04266652

Last Updated: 2020-07-22

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: PHASE4
• Total Enrollment: 14 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2018-01-06
• Study Completion Date: 2020-09-30

Brief Summary

assess and compare the efficacy and safety of autogenous tooth roots for lateral alveolar ridge augmentation with staged implant placement in comparison to autogenous bone block.

Detailed Description

A total of 14 patients in need of implant therapy and lateral ridge augmentation were allocated to parallel groups receiving either 1) healthy autogenous tooth roots (e.g. retained wisdom or impacted teeth or 2) cortical autogenous bone blocks harvested from the retromolar area. After 26 weeks of submerged healing the horizontal bone gain were assessed both clinically and radiographically. A core biopsy was taken during the implant placement to assess the histology of the newly formed bone.

Conditions

Augmentation

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Autogenous bone block

the monocortical block grafts were harvested from the retromolar region (i.e. linea oblique) by using of rotating (i.e. carbide burs)

Group Type: EXPERIMENTAL

autogenous bone block

Intervention Type: PROCEDURE

autogenous bone block were used to increase the bone width

Tooth block

In the first group, a second mucoperiosteal flap was elevated to surgically remove the respective wisdom tooth. After its removal and during the same surgery, the crown was decapitated at the cemento -enamel junction using a rotating carbide bur under gentle sterile saline cooling and the exposed pulp was preserved. The separated tooth root was adapted to match the size and shape of the defect area. To improve ankylosis between the graft and the defect site, the layer of cementum at the respective downward aspects of the root was carefully removed using a diamond bur until the underlying dentin was entirely exposed

Group Type: EXPERIMENTAL

tooth block

Intervention Type: PROCEDURE

tooth root blocks were used to increase the bone width

Interventions

tooth block

tooth root blocks were used to increase the bone width

Intervention Type: PROCEDURE

autogenous bone block

autogenous bone block were used to increase the bone width

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

1. Candidate for lateral ridge augmentation

2. Insufficient bone ridge width at the recipient site for implant placement

3. Sufficient bone height at the recipient site for implant placement

4. Healthy oral mucosa, at least 3 mm keratinized tissue.

5. Presence of wisdom teeth free from periapical infection.

6. Missing maxillary or mandibular tooth with moderate horizontal defect (4-8) according to cologne classification

Exclusion Criteria

• 1) Patients are systemically free according to Modified Cornell Medical Index 2) smokers patients. 3) Pregnant or lactating women.

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Ain Shams University

OTHER

Sponsor Role: lead

Responsible Party

Doaa Adel Salah Khattab

Lecturer Periodontology, Faculty of Dentistry

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Ain Shams University

Cairo, Abbassia, Egypt

Site Status: RECRUITING

Countries

Egypt

Facility Contacts

Laila El Raee, B.D.S

Role: primary

lelraee@msa.eun.eg

+201280967588

Other Identifiers

121734

Identifier Type: -

Identifier Source: org_study_id