Demineralized Whole-tooth vs Demineralized Particulate Dentin Grafts in Alveolar Ridge Preservation
NCT ID: NCT05336149
Last Updated: 2022-04-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
20 participants
INTERVENTIONAL
2022-06-30
2023-06-30
Brief Summary
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Detailed Description
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Alveolar ridge preservation is a procedure that attempts to reduce bone dimensional changes that naturally take place following tooth extraction. To overcome this problem, various approaches using various grafting materials and/or covering membranes have been proposed with varied success. The extracted tooth is no longer considered as clinical waste, it has been explored as an appropriate source for autogenous graft substitute. This idea emerged due to the shared embryonic origin of bone and teeth as well as the similarities in chemical structure as dentin is composed of 30-35% organic part and 65-70% inorganic part in comparison to alveolar bone, with inorganic and organic parts of 35% and 65% respectively. Both whole-tooth and particulate forms has been utilized for alveolar ridge preservation or augmentation but the superiority of one form over the other is not yet clear.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Whole-tooth dentin graft
The extracted tooth will be prepared as whole-tooth dentin graft and inserted in the extraction socket.
Alveolar ridge preservation using whole-tooth dentin graft
Minimally-traumatic extraction of non-restorable teeth then grafting with whole-tooth dentin graft
Particulate dentin graft
The extracted tooth will be prepared as particulate dentin graft and inserted in the extraction socket.
Alveolar ridge preservation using particulate dentin graft
Minimally-traumatic extraction of non-restorable teeth then grafting with particulate dentin graft
Interventions
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Alveolar ridge preservation using whole-tooth dentin graft
Minimally-traumatic extraction of non-restorable teeth then grafting with whole-tooth dentin graft
Alveolar ridge preservation using particulate dentin graft
Minimally-traumatic extraction of non-restorable teeth then grafting with particulate dentin graft
Eligibility Criteria
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Inclusion Criteria
* single-rooted teeth
* Patients at least 18 years or older
* Motivated patients, agree to sign informed consent and complete the follow-up period
Exclusion Criteria
* active infection at extraction site
* Smokers
* systemic conditions affecting healing (e.g. diabetes, medications as bisphosphonates...)
18 Years
60 Years
ALL
Yes
Sponsors
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Cairo University
OTHER
Responsible Party
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Ahmed Mohamed AbdelRaouf Hussein
Principal investigator
Locations
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Cairo University
Cairo, , Egypt
Countries
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Central Contacts
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Other Identifiers
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42022
Identifier Type: -
Identifier Source: org_study_id
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