the Effect of Hyaluronic Acid on a Prefabricated CAD-CAM Bone Blocks for Ridge Augmentation
NCT ID: NCT06395818
Last Updated: 2024-12-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
10 participants
INTERVENTIONAL
2023-03-29
2024-12-06
Brief Summary
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Side I: prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using hyaluronic acid \* Side II: prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using saline solution Both blocks are fixed with osteosynthesis screws, covered with non resorbable membranes\*\* The membranes will be removed after 6 months, dental implants will be placed and core biopsy will be collected from the site of the implant placement for histologic evaluation
Detailed Description
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. group I: prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using hyaluronic acid group II: prefabricated CAD-CAM allogeneic bone block sterilized with gamma rays hydrated using saline solution under LA mucoperiosteal flap will be elevated to expose the atrophic ridge then the prefabricated CAD-CAM allogenic block either mixed with hyaluronic acid (group I) or saline (group II) will be fixed in its position with titanium miniscrews , The block was coated with a nonporous d-PTFE membrane then closure of flap with nylon second stage: 6 months later exposure of alveolar ridge core biopsy was taken for histological study then insertion of titanium implants.
the aim of the study is to investigate the effect of hyaluronic acid on a prefabricated CAD- CAM bone blocks for ridge augmentation radiographically and histologically.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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prefabricated CAD-CAM allogeneic bone block hydrated using hyaluronic acid
mucoperiosteal flap will be elevated to expose the atrophic ridge then the prefabricated CAD-CAM allogenic block will be fixed in its position with titanium miniscrews , The block was coated with a nonporous d-PTFE membrane
prefabricated CAD-CAM allogeneic bone block hydrated using hyaluronic acid
exposure of atrophic posterior mandibular ridge, augmentation with CAD-CAM prefabricated allogenic bone block which fixed with titanium screws ,The block was coated with a nonporous d-PTFE membrane
prefabricated CAD-CAM allogeneic bone block sterilized hydrated using saline solution
mucoperiosteal flap will be elevated to expose the atrophic ridge then the prefabricated CAD-CAM allogenic block will be fixed in its position with titanium miniscrews ,The block was coated with a nonporous d-PTFE membrane
prefabricated CAD-CAM allogeneic bone block sterilized hydrated using saline solution
exposure of atrophic posterior mandibular ridge, augmentation with CAD-CAM prefabricated allogenic bone block which fixed with titanium screws. The block was coated with a nonporous d-PTFE membrane
Interventions
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prefabricated CAD-CAM allogeneic bone block hydrated using hyaluronic acid
exposure of atrophic posterior mandibular ridge, augmentation with CAD-CAM prefabricated allogenic bone block which fixed with titanium screws ,The block was coated with a nonporous d-PTFE membrane
prefabricated CAD-CAM allogeneic bone block sterilized hydrated using saline solution
exposure of atrophic posterior mandibular ridge, augmentation with CAD-CAM prefabricated allogenic bone block which fixed with titanium screws. The block was coated with a nonporous d-PTFE membrane
Eligibility Criteria
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Inclusion Criteria
* Posterior atrophic mandibular ridge indicated for horizontal and vertical ridge augmentation for dental implant placement.
* Good oral hygiene
Exclusion Criteria
* Heavy smoking.
* Poor oral hygiene.
* Traumatic occlusion, sever para-functional habits (ex. bruxism, clenching,)
40 Years
65 Years
ALL
Yes
Sponsors
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Tanta University
OTHER
Responsible Party
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Mohamed Hamdy Helal
lecturer of oral medicine, periodontology, oral diagnosis and radiology department
Principal Investigators
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mohamed h helal, lecturer
Role: PRINCIPAL_INVESTIGATOR
Tanta University
Locations
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Faculty of Dentistry, Tanta University
Tanta, , Egypt
Countries
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References
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Helal MH, Sheta MS, Alsherif AA, Hassan MA, Aboushelib MN, Ghouraba RF. The Effectiveness of Hyaluronic Acid on Prefabricated CAD CAM Bone Blocks for Ridge Augmentation: A Split Mouth Study. Clin Implant Dent Relat Res. 2025 Apr;27(2):e70035. doi: 10.1111/cid.70035.
Other Identifiers
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6789
Identifier Type: -
Identifier Source: org_study_id