Autogenous Tooth Graft for Ridge Augmentation

NCT ID: NCT06416605

Last Updated: 2024-05-16

Basic Information

• Recruitment Status: ACTIVE_NOT_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 28 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-01-01
• Study Completion Date: 2024-12-30

Brief Summary

This study is designed to evaluate the clinical and radiographical outcome of tooth shell for alveolar ridge reconstruction in maxilla as an alternative to traditional autologous bone shell graft.

Detailed Description

twenty eight patients with one or two maxillary extracted teeth in need for horizontal bone augmentation and implant placement will be selected from the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University patients will be divided into two equal groups:

• Group I: Horizontal bone augmentation will be done by bone shell technique.

• Group II: Horizontal bone augmentation will be done by autogenous tooth shell technique.

Evaluation:

A-Clinical evaluation:

• All patients were followed up on a weekly basis for the first postoperative month, then monthly for the rest of the postoperative period (6months) until implantation.
• The patients were evaluated regarding pain, edema and hematoma at recipient and donor sites as well as healing of the mucosa.
• A neurosensory evaluation was carried out at each clinical check up by asking the patient if there were any areas of hypoesthesia, numbness or tingling in the lower lip and chin at the side of the donor site.

B-Radiographic evaluation

•Cone beam computed tomography (CBCT) were made immediately and 6 months post-operative to assess the alveolar bone in all three planes of space before implant placement. According to the measurements obtained from CBCT, appropriate implant size and length will be chosen and placed 6 months postoperative after removal of the micro screws.

Radiographic analysis:

Linear measurements of alveolar bone width were taken using CBCT scan at three stages; prior to grafting (T0) and immediately (T1), and 4 months post grafting (T2). Then three horizontal alveolar width measurements (crestal, middle and apical) were recorded at T0, T2 and T1. The measurement was performed with fixed points each time, the buccolingual width was measured at different levels. At the bone crest, 3mm from the bone crest and 6mm from the bone crest. The measurements were tabulated for statistical analysis.

Conditions

Dental Implant

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: TRIPLE

Study Groups

group A

Horizontal bone augmentation will be done by bone shell technique

Group Type: EXPERIMENTAL

Maxillary Alveolar Ridge Augmentation

Intervention Type: PROCEDURE

using tooth graft or bone graft to increase alveolar ridge width to be able to insert dental implant

group B

Horizontal bone augmentation will be done by autogenous tooth shell technique

Group Type: EXPERIMENTAL

Maxillary Alveolar Ridge Augmentation

Intervention Type: PROCEDURE

using tooth graft or bone graft to increase alveolar ridge width to be able to insert dental implant

Interventions

Maxillary Alveolar Ridge Augmentation

using tooth graft or bone graft to increase alveolar ridge width to be able to insert dental implant

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• 1- One or two maxillary extracted teeth with crestal bone width of 4 mm or less.

2- Age ranging from 18_50 years 3- 3- Adequate oral hygiene. 4- Non smoking patients. 5-Free from any pathological lesions related to the tooth to be extracted. 6- Physically fit to withstand the whole procedure.

Exclusion Criteria

• 1- Active infection in the site to be treated. 2- Patients on chemotherapy or radiotherapy. 3- Alcohol or drug abuse. 4- Patients who have systemic disorders that interfere with bone healing {uncontrolled diabetes mellitus, autoimmune disease,

• etc.} 5- Pregnancy. 6- Patients with bone disease. 7- Patients with parafunctional habits

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Mansoura University

OTHER

Sponsor Role: lead

Responsible Party

Heba Elsheikh

Assistant Professor of Oral and Maxillofacial Surgery

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Heba Elsheikh

Al Mansurah, , Egypt

Countries

Egypt

References

Awad KAI, Tawik MA, Hussein MM, El-Farag SAA, Sameaa SESA. Tooth shell versus bone shell technique for horizontal maxillary alveolar ridge augmentation. BMC Oral Health. 2025 Apr 25;25(1):642. doi: 10.1186/s12903-025-05940-4.

Reference Type: DERIVED

PMID: 40281533 (View on PubMed)

Other Identifiers

A03030123

Identifier Type: -

Identifier Source: org_study_id