SEx-specific Differences in Cardiac Surgery Patients (SECS).
NCT ID: NCT06554925
Last Updated: 2024-08-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
10000 participants
OBSERVATIONAL
2022-03-01
2031-03-01
Brief Summary
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Detailed Description
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Given the higher mortality and morbidity in females after cardiac surgery, as well as the abovementioned sex differences, it is likely that females require different perioperative care than males, for better and faster recovery.
The investigators hypothesise that females require different perioperative care (pathways) compared to males when undergoing cardiac surgery. The investigators would therefore like to investigate which factors are different in female and male patients, by setting up a database of perioperative parameters. By identifying the factors that adversely affect morbidity and mortality in females and linking these parameters, the investigators would like to improve outcome in fmales after cardiac surgery.
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Female
Female sex undergoing cardiac surgery
Cardiac surgery
The difference in males and females undergoing cardiac surgery of all types
Male
Male sex undergoing cardiac surgery
Cardiac surgery
The difference in males and females undergoing cardiac surgery of all types
Interventions
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Cardiac surgery
The difference in males and females undergoing cardiac surgery of all types
Eligibility Criteria
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Inclusion Criteria
* All patients who underwent cardiac surgery from 1 January 1998 in the AUMC, location VUmc, until 1 June 2021.
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Jennifer Breel
OTHER
Responsible Party
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Jennifer Breel
Research coordinator
Principal Investigators
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Markus W Hollmann, Professor
Role: PRINCIPAL_INVESTIGATOR
Anesthesiology and Pain Medicine, Amsterdam Medical Center
Locations
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Academic Medical Center
Amsterdam, North Holland, Netherlands
Countries
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Central Contacts
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Facility Contacts
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References
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Cho L, Kibbe MR, Bakaeen F, Aggarwal NR, Davis MB, Karmalou T, Lawton JS, Ouzounian M, Preventza O, Russo AM, Shroyer AW, Zwischenberger BA, Lindley KJ. Cardiac Surgery in Women in the Current Era: What Are the Gaps in Care? Circulation. 2021 Oct 5;144(14):1172-1185. doi: 10.1161/CIRCULATIONAHA.121.056025. Epub 2021 Oct 4.
Dixon LK, Di Tommaso E, Dimagli A, Sinha S, Sandhu M, Benedetto U, Angelini GD. Impact of sex on outcomes after cardiac surgery: A systematic review and meta-analysis. Int J Cardiol. 2021 Nov 15;343:27-34. doi: 10.1016/j.ijcard.2021.09.011. Epub 2021 Sep 11.
Nanegrungsunk D, Patel S, Jan T, Ngai JY. Preoperative Care Practice for Female Cardiac Patients: A Survey From the Society of Cardiovascular Anesthesiologists. J Cardiothorac Vasc Anesth. 2022 Mar;36(3):920-921. doi: 10.1053/j.jvca.2021.09.054. Epub 2021 Oct 3. No abstract available.
Peters SAE, Kluin J. Why do women do worse after coronary artery bypass grafting? Eur Heart J. 2021 Dec 28;43(1):29-31. doi: 10.1093/eurheartj/ehab617. No abstract available.
Other Identifiers
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W22_050 # 22.081
Identifier Type: -
Identifier Source: org_study_id
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