Myocardial and Renal Dysfunction by Oxidative Stress Caused by Cardiac Surgery

NCT ID: NCT02394405

Last Updated: 2019-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

21 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-03-31

Study Completion Date

2018-12-31

Brief Summary

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Assessment of the severity of oxidative stress caused by the on-pump and off-pump cardiac surgery using mtDNA, nDNA, carbonilated proteins, nitrotyrosine, oxy-LDL, S100b-protein.

Detailed Description

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Conditions

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Reperfusion Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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valve surgery

valve plasty/replacement surgery

No interventions assigned to this group

off-pump CABG

off-pump CABG

No interventions assigned to this group

CPB-CABG

CABG with CardioPulmonal Bypass

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* shedduled CABG

Exclusion Criteria

* stroke befor surgery
* miocardial infarction 6 monthes befor surgery
* dementia
* liver cirrhosis
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Moscow Regional Research and Clinical Institute (MONIKI)

OTHER_GOV

Sponsor Role lead

Responsible Party

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Valery V. Likhvantsev, Professor

senior researcher

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy

Moscow, , Russia

Site Status

Countries

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Russia

Other Identifiers

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OD-CABG-2015

Identifier Type: -

Identifier Source: org_study_id

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