Biomarkers in Thoracic Aorta Surgery

NCT ID: NCT04689139

Last Updated: 2024-09-19

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

132 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-01

Study Completion Date

2022-05-01

Brief Summary

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Biomarkers can play a vital role in prognosing the perioperative complications in thoracic aorta surgery. The goal of a study is to determine the correlation between intraoperative level of certain biomarkers and total amount of peroperative complications.

Detailed Description

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This study aims to assess the association between levels of biomarkers and postoperative complications in patients after thoracic and thoracoabdominal aortic reconstruction.

Conditions

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Aortic Aneurysm Thoracoabdominal Aneurysm Aortic Dissection Complication

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Thoracic aorta surgery patients

Blood samples on proadrenomedullin, presepsin, NT-proBNP, Troponin I, procalcitonin are acquired

Group Type EXPERIMENTAL

blood sample tests for determination of biomarkers levels

Intervention Type DIAGNOSTIC_TEST

Using of proadrenomedullin, presepsin, NT-proBNP, Troponin I to determine the correlation of perioperative complications.

Interventions

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blood sample tests for determination of biomarkers levels

Using of proadrenomedullin, presepsin, NT-proBNP, Troponin I to determine the correlation of perioperative complications.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Elective thoracic and thoracoabdominal surgery

Exclusion Criteria

* Hemolysis in blood sample
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Petrovsky National Research Centre of Surgery

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Boris Akselrod, Professor

Role: STUDY_DIRECTOR

Petrovsky NRCS

Locations

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Petrovsky Research National Centre of Surgery ( Petrovsky NRCS)

Moscow, , Russia

Site Status

Countries

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Russia

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Related Links

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https://russjcardiol.elpub.ru/jour/article/view/5314/4231

Assessing the significance of some biomarkers in perioperative period after thoracic aortic reconstruction

Other Identifiers

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039420200002

Identifier Type: -

Identifier Source: org_study_id

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