Vascular Events In Surgery patIents cOhort evaluatioN - Cardiac Surgery
NCT ID: NCT01842568
Last Updated: 2025-07-31
Study Results
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Basic Information
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COMPLETED
15989 participants
OBSERVATIONAL
2013-05-31
2025-07-31
Brief Summary
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This study will determine the current incidence of major complications in a representative sample of 15,000 contemporary adult patients undergoing heart surgery. Knowing the current burden of complications will inform clinicians, administrators, government and granting agencies about resources required to address the problem. This study will also establish the role of measuring heart injury markers to identify important heart injury after heart surgery and the proportion that would go undetected without routine heart injury marker monitoring. This information will facilitate further studies of timely interventions. In summary, the VISION Cardiac Surgery Study addresses fundamental questions that will have profound public health implications given the millions of adults worldwide who undergo heart surgery annually.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
2. Patients who have undergone cardiac surgery. This includes coronary artery bypass grafting and all open heart procedures such as valvular repairs/replacement.
Exclusion Criteria
2. Patients who have undergone an isolated pericardial window, pericardiectomy, permanent pacemaker or defibrillator implantation.
18 Years
ALL
No
Sponsors
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Abbott Diagnostics Division
INDUSTRY
Population Health Research Institute
OTHER
Responsible Party
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Andre Lamy
Professor and Cardiac Surgeon
Principal Investigators
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P.J. Devereaux, MD, PhD
Role: STUDY_CHAIR
McMaster University
Andre Lamy, MD
Role: PRINCIPAL_INVESTIGATOR
McMaster University
Richard Whitlock, MD
Role: PRINCIPAL_INVESTIGATOR
McMaster University
Locations
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Ronald Reagan Medical Centre, UCLA
Los Angeles, California, United States
Royal Prince Alfred Hospital
Sydney, New South Wales, Australia
Hospital de Clínicas de Porto Alegre - HCPA
Porto Alegre, Rio Grande do Sul, Brazil
Instituto de Cardiologia do RS
Porto Alegre, Rio Grande do Sul, Brazil
INCOR
São Paulo, , Brazil
Hamilton Health Sciences
Hamilton, Ontario, Canada
Kingston General Hospital
Kingston, Ontario, Canada
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
First Teaching Hospital
Xinjiang, , China
Prince of Wales Hospital
Shatin, Hong Kong, SAR, Hong Kong
Santa Maria Hospital, GVM Care and Research
Bari, , Italy
University of Bari "Aldo Moro"
Bari, , Italy
San Raffaele Scientific Institute
Milan, , Italy
Institut Jantung Negara Sdn. Bhd.
Kuala Lumpur, , Malaysia
University of Malaya Medical Centre
Kuala Lumpur, , Malaysia
Department of Cardiovascular Surgery, Medical University of Gdansk
Gdansk, , Poland
Federal State Budgetary Institution "Research Institute for Complex Issues of Cardiovascular Diseases"
Kemerovo, , Russia
Research Institute of Circulation Pathology
Novosibirsk, , Russia
Hospital de la Santa Creu i Sant Pau
Barcelona, , Spain
Essex Cardiothoracic Centre, Basildon and Thurrock University NHS Trust
Basildon, Essex, United Kingdom
Blackpool Teaching Hospitals NHS Foundation Trust
Blackpool, Lancashire, United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation Trust
Liverpool, Merseyside, United Kingdom
BHF Centre of Cardiovascular Science, University of Edinburgh
Edinburgh, , United Kingdom
New Cross Hospital
Wolverhampton, , United Kingdom
Countries
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References
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Devereaux PJ, Lamy A, Chan MTV, Allard RV, Lomivorotov VV, Landoni G, Zheng H, Paparella D, McGillion MH, Belley-Cote EP, Parlow JL, Underwood MJ, Wang CY, Dvirnik N, Abubakirov M, Fominskiy E, Choi S, Fremes S, Monaco F, Urrutia G, Maestre M, Hajjar LA, Hillis GS, Mills NL, Margari V, Mills JD, Billing JS, Methangkool E, Polanczyk CA, Sant'Anna R, Shukevich D, Conen D, Kavsak PA, McQueen MJ, Brady K, Spence J, Le Manach Y, Mian R, Lee SF, Bangdiwala SI, Hussain S, Borges FK, Pettit S, Vincent J, Guyatt GH, Yusuf S, Alpert JS, White HD, Whitlock RP; VISION Cardiac Surgery Investigators. High-Sensitivity Troponin I after Cardiac Surgery and 30-Day Mortality. N Engl J Med. 2022 Mar 3;386(9):827-836. doi: 10.1056/NEJMoa2000803.
Spence J, Bosch J, Chongsi E, Lee SF, Thabane L, Mendoza P, Belley-Cote E, Whitlock R, Brady K, McIntyre WF, Lamy A, Devereaux PJ. Standardized Assessment of Global activities in the Elderly scale in adult cardiac surgery patients. Br J Anaesth. 2021 Oct;127(4):539-546. doi: 10.1016/j.bja.2021.05.037. Epub 2021 Jul 28.
McGillion MH, Henry S, Busse JW, Ouellette C, Katz J, Choiniere M, Lamy A, Whitlock R, Pettit S, Hare J, Gregus K, Brady K, Dvirnik N, Yang SS, Parlow J, Dumerton-Shore D, Gilron I, Buckley DN, Shanthanna H, Carroll SL, Coyte PC, Ebrahim S, Isaranuwatchai W, Guerriere DN, Hoch J, Khan J, MacDermid J, Martorella G, Victor JC, Watt-Watson J, Howard-Quijano K, Mahajan A, Chan MTV, Clarke H, Devereaux PJ. Examination of psychological risk factors for chronic pain following cardiac surgery: protocol for a prospective observational study. BMJ Open. 2019 Mar 1;9(2):e022995. doi: 10.1136/bmjopen-2018-022995.
Ackland GL, Abbott TEF, Cain D, Edwards MR, Sultan P, Karmali SN, Fowler AJ, Whittle JR, MacDonald NJ, Reyes A, Paredes LG, Stephens RCM, Del Arroyo AG, Woldman S, Archbold RA, Wragg A, Kam E, Ahmad T, Khan AW, Niebrzegowska E, Pearse RM. Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non-cardiac surgery. Br J Anaesth. 2019 Feb;122(2):180-187. doi: 10.1016/j.bja.2018.09.002. Epub 2018 Oct 2.
Other Identifiers
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VISION Cardiac Surgery
Identifier Type: -
Identifier Source: org_study_id
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