Relationship Between Microcirculatory Flow Alterations and Tissue Metabolism

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-11-30

Study Completion Date

2008-11-30

Brief Summary

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The purpose of this study is to correlate microcirculatory flow and rectal anaerobe cellular CO2 production in patients after cardiac surgery. The hypothesis is that such a correlation exists.

Detailed Description

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Sidestream Darkfield imaging is used to determine rectal microcirculatory flow in patients after postoperative cardiac surgery. At the same time PCO2 gap is established by monitoring rectal CO2 (tonometry) and arterial CO2 After initial enrollment and first analysis we also includes a control group with equal inclusion criteria for sublingual SDF imaging.

Conditions

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Cardiac Surgery

Keywords

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microcirculation cardiac surgery metabolism capnometry

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* cardiac surgery
* informed consent
* age \> 18

Exclusion Criteria

* pregnancy
* off pump procedure
* rectal fecal contamination

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Medical Center Leeuwarden

Principal Investigators

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E.C. Boerma, MD

Role: PRINCIPAL_INVESTIGATOR

Frisius Medisch Centrum

Locations

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Department of ICU

Leeuwarden, PO Box 888, Netherlands

Site Status

Countries

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Netherlands

References

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Boerma EC, Mathura KR, van der Voort PH, Spronk PE, Ince C. Quantifying bedside-derived imaging of microcirculatory abnormalities in septic patients: a prospective validation study. Crit Care. 2005;9(6):R601-6. doi: 10.1186/cc3809. Epub 2005 Sep 22.

Reference Type BACKGROUND

PMID: 16280059 (View on PubMed)

Other Identifiers

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ABR 19609

Identifier Type: -

Identifier Source: secondary_id

TPO 503